The use of potentially inappropriate medications and changes in quality of life among older nursing home residents

Sana’ MH Al Aqqad, Li Li Chen, Asrul Akmal Shafie, Mohamed Azmi Hassali, Balamurugan Tangiisuran Pharmacy Practice Research Group, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia Background: Nursing home residents are mainly older people with multiple diseas...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Al Aqqad S MH, Chen LL, Shafie AA, Hassali MA, Tangiisuran B
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Elderly Health Related Quality of Life Nursing homes Patient safety Potentially inappropriate medications Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/cddcb4da4d3f465bbafbb2b0c7b5a28e
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:cddcb4da4d3f465bbafbb2b0c7b5a28e
record_format	dspace
spelling	oai:doaj.org-article:cddcb4da4d3f465bbafbb2b0c7b5a28e2021-12-02T04:16:06ZThe use of potentially inappropriate medications and changes in quality of life among older nursing home residents1178-1998https://doaj.org/article/cddcb4da4d3f465bbafbb2b0c7b5a28e2014-01-01T00:00:00Zhttps://www.dovepress.com/the-use-of-potentially-inappropriate-medications-and-changes-in-qualit-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Sana’ MH Al Aqqad, Li Li Chen, Asrul Akmal Shafie, Mohamed Azmi Hassali, Balamurugan Tangiisuran Pharmacy Practice Research Group, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia Background: Nursing home residents are mainly older people with multiple diseases and taking multiple medications. The quality use of medication and its association with health related quality of life (HRQoL) have not been reported in Malaysia. This study aims to investigate the association between the use of potentially inappropriate medications (PIMs) and the changes observed in the HRQoL among older nursing home residents. Methods: A prospective follow up study was conducted at four nongovernmental organization nursing homes in Penang, Malaysia. Older residents (≥65 years old) taking at least one prescribed medication were included. Residents with PIMs were identified by using Screening Tool of Older Person's potentially inappropriate Prescriptions (STOPP) criteria. HRQoL was assessed using EuroQol-5 dimension (EQ-5D) and EuroQol-visual analog scale (EQ-VAS) at baseline and after a 3-month follow up. The association of PIMs with HRQoL was analyzed using Mann-Whitney U test. Results: The median age of the 211 participants was 77 years (interquartile range 72–82 years) and the median number of prescription medicines was four (interquartile range three to six). The prevalence of PIMs was 23.7% and 18.6% at baseline and 3 months later, respectively. The most commonly prescribed PIMs in decreasing order were first generation antihistamine, prescriptions of duplicate drug class, glibenclamide with type 2 diabetes mellitus, and anticholinergic to treat extrapyramidal side effects of neuroleptic medications. At baseline, there was no significant difference among residents with or without PIMs in each bracket of EQ-5D, EQ-5D index, or EQ-VAS scores. Comparison of the differences in the mean score index of EQ-5D between baseline and after 3 months also showed no statistically significant differences. Conclusion: PIMs were found to be relatively common among older nursing home residents. However, no significant changes were observed in HRQoL among these residents. Further studies with a bigger sample size and longer follow up period are required to establish this association. Keywords: elderly, health related quality of life, patient safetyAl Aqqad S MHChen LLShafie AAHassali MATangiisuran BDove Medical PressarticleElderlyHealth Related Quality of LifeNursing homesPatient safetyPotentially inappropriate medicationsGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 9, Pp 201-207 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Elderly Health Related Quality of Life Nursing homes Patient safety Potentially inappropriate medications Geriatrics RC952-954.6
spellingShingle	Elderly Health Related Quality of Life Nursing homes Patient safety Potentially inappropriate medications Geriatrics RC952-954.6 Al Aqqad S MH Chen LL Shafie AA Hassali MA Tangiisuran B The use of potentially inappropriate medications and changes in quality of life among older nursing home residents
description	Sana’ MH Al Aqqad, Li Li Chen, Asrul Akmal Shafie, Mohamed Azmi Hassali, Balamurugan Tangiisuran Pharmacy Practice Research Group, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia Background: Nursing home residents are mainly older people with multiple diseases and taking multiple medications. The quality use of medication and its association with health related quality of life (HRQoL) have not been reported in Malaysia. This study aims to investigate the association between the use of potentially inappropriate medications (PIMs) and the changes observed in the HRQoL among older nursing home residents. Methods: A prospective follow up study was conducted at four nongovernmental organization nursing homes in Penang, Malaysia. Older residents (≥65 years old) taking at least one prescribed medication were included. Residents with PIMs were identified by using Screening Tool of Older Person's potentially inappropriate Prescriptions (STOPP) criteria. HRQoL was assessed using EuroQol-5 dimension (EQ-5D) and EuroQol-visual analog scale (EQ-VAS) at baseline and after a 3-month follow up. The association of PIMs with HRQoL was analyzed using Mann-Whitney U test. Results: The median age of the 211 participants was 77 years (interquartile range 72–82 years) and the median number of prescription medicines was four (interquartile range three to six). The prevalence of PIMs was 23.7% and 18.6% at baseline and 3 months later, respectively. The most commonly prescribed PIMs in decreasing order were first generation antihistamine, prescriptions of duplicate drug class, glibenclamide with type 2 diabetes mellitus, and anticholinergic to treat extrapyramidal side effects of neuroleptic medications. At baseline, there was no significant difference among residents with or without PIMs in each bracket of EQ-5D, EQ-5D index, or EQ-VAS scores. Comparison of the differences in the mean score index of EQ-5D between baseline and after 3 months also showed no statistically significant differences. Conclusion: PIMs were found to be relatively common among older nursing home residents. However, no significant changes were observed in HRQoL among these residents. Further studies with a bigger sample size and longer follow up period are required to establish this association. Keywords: elderly, health related quality of life, patient safety
format	article
author	Al Aqqad S MH Chen LL Shafie AA Hassali MA Tangiisuran B
author_facet	Al Aqqad S MH Chen LL Shafie AA Hassali MA Tangiisuran B
author_sort	Al Aqqad S MH
title	The use of potentially inappropriate medications and changes in quality of life among older nursing home residents
title_short	The use of potentially inappropriate medications and changes in quality of life among older nursing home residents
title_full	The use of potentially inappropriate medications and changes in quality of life among older nursing home residents
title_fullStr	The use of potentially inappropriate medications and changes in quality of life among older nursing home residents
title_full_unstemmed	The use of potentially inappropriate medications and changes in quality of life among older nursing home residents
title_sort	use of potentially inappropriate medications and changes in quality of life among older nursing home residents
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/cddcb4da4d3f465bbafbb2b0c7b5a28e
work_keys_str_mv	AT alaqqadsmh theuseofpotentiallyinappropriatemedicationsandchangesinqualityoflifeamongoldernursinghomeresidents AT chenll theuseofpotentiallyinappropriatemedicationsandchangesinqualityoflifeamongoldernursinghomeresidents AT shafieaa theuseofpotentiallyinappropriatemedicationsandchangesinqualityoflifeamongoldernursinghomeresidents AT hassalima theuseofpotentiallyinappropriatemedicationsandchangesinqualityoflifeamongoldernursinghomeresidents AT tangiisuranb theuseofpotentiallyinappropriatemedicationsandchangesinqualityoflifeamongoldernursinghomeresidents AT alaqqadsmh useofpotentiallyinappropriatemedicationsandchangesinqualityoflifeamongoldernursinghomeresidents AT chenll useofpotentiallyinappropriatemedicationsandchangesinqualityoflifeamongoldernursinghomeresidents AT shafieaa useofpotentiallyinappropriatemedicationsandchangesinqualityoflifeamongoldernursinghomeresidents AT hassalima useofpotentiallyinappropriatemedicationsandchangesinqualityoflifeamongoldernursinghomeresidents AT tangiisuranb useofpotentiallyinappropriatemedicationsandchangesinqualityoflifeamongoldernursinghomeresidents
_version_	1718401397952610304

The use of potentially inappropriate medications and changes in quality of life among older nursing home residents

Ejemplares similares