<i>CCNE1</i> and <i>E2F1</i> Partially Suppress G1 Phase Arrest Caused by Spliceostatin A Treatment

The potent splicing inhibitor spliceostatin A (SSA) inhibits cell cycle progression at the G1 and G2/M phases. We previously reported that upregulation of the p27 cyclin-dependent kinase inhibitor encoded by <i>CDKN1B</i> and its C-terminal truncated form, namely p27*, which is translate...

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Autores principales: Kei Kikuchi, Daisuke Kaida
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/cddfb050680e47229d9dd0938f687848
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