Deoxyshikonin isolated from Arnebia euchroma inhibits colorectal cancer by down-regulating the PI3K/Akt/mTOR pathway

Context: Shikonins, a series of natural occurring naphthoquinones extracted from Arnebia euchroma (Royle) Jonst. (Boraginaceae), have antitumor activities and low toxicity. Objective: To illuminate potential activity and mechanism of shikonins against colorectal cancer (CRC). Materials and methods:...

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Autores principales: Yuzhen Zhu, Yu Zhong, Xun Long, Zhu Zhu, Yu Zhou, Hua Ye, Xiaobin Zeng, Xuebao Zheng
Formato: article
Lenguaje:EN
Publicado: Taylor & Francis Group 2019
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Acceso en línea:https://doaj.org/article/cde1ce3a5a4042c9af2856ceb8b1a6e3
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