Argininosuccinate lyase is a metabolic vulnerability in breast development and cancer

Argininosuccinate lyase is a metabolic vulnerability in breast development and cancer

Abstract Epithelial-to-mesenchymal transition (EMT) is fundamental to both normal tissue development and cancer progression. We hypothesized that EMT plasticity defines a range of metabolic phenotypes and that individual breast epithelial metabolic phenotypes are likely to fall within this phenotypi...

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Bibliographic Details
Main Authors: Sigurdur Trausti Karvelsson, Qiong Wang, Bylgja Hilmarsdottir, Arnar Sigurdsson, Siver Andreas Moestue, Gunhild Mari Mælandsmo, Skarphedinn Halldorsson, Steinn Gudmundsson, Ottar Rolfsson
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/cdfa07e4bd6d4ad0a6994536dab48cac
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