Neural signatures of hyperdirect pathway activity in Parkinson’s disease
In Parkinson’s disease (PD), beta frequency oscillations are synchronised across the cortico-basal-ganglia circuit. The authors show in human participants that high beta frequencies propagate from the cortex to the basal ganglia via the hyperdirect pathway, indicating a pathophysiological role for t...
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Nature Portfolio
2021
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oai:doaj.org-article:cdfc65b27df649a2be40ee8e183add842021-12-02T15:25:36ZNeural signatures of hyperdirect pathway activity in Parkinson’s disease10.1038/s41467-021-25366-02041-1723https://doaj.org/article/cdfc65b27df649a2be40ee8e183add842021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25366-0https://doaj.org/toc/2041-1723In Parkinson’s disease (PD), beta frequency oscillations are synchronised across the cortico-basal-ganglia circuit. The authors show in human participants that high beta frequencies propagate from the cortex to the basal ganglia via the hyperdirect pathway, indicating a pathophysiological role for this pathway in PD.Ashwini OswalChunyan CaoChien-Hung YehWolf-Julian NeumannJames GratwickeHarith AkramAndreas HornDianyou LiShikun ZhanChao ZhangQiang WangLudvic ZrinzoTom FoltyniePatricia LimousinRafal BogaczBomin SunMasud HusainPeter BrownVladimir LitvakNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021) |
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Science Q Ashwini Oswal Chunyan Cao Chien-Hung Yeh Wolf-Julian Neumann James Gratwicke Harith Akram Andreas Horn Dianyou Li Shikun Zhan Chao Zhang Qiang Wang Ludvic Zrinzo Tom Foltynie Patricia Limousin Rafal Bogacz Bomin Sun Masud Husain Peter Brown Vladimir Litvak Neural signatures of hyperdirect pathway activity in Parkinson’s disease |
description |
In Parkinson’s disease (PD), beta frequency oscillations are synchronised across the cortico-basal-ganglia circuit. The authors show in human participants that high beta frequencies propagate from the cortex to the basal ganglia via the hyperdirect pathway, indicating a pathophysiological role for this pathway in PD. |
format |
article |
author |
Ashwini Oswal Chunyan Cao Chien-Hung Yeh Wolf-Julian Neumann James Gratwicke Harith Akram Andreas Horn Dianyou Li Shikun Zhan Chao Zhang Qiang Wang Ludvic Zrinzo Tom Foltynie Patricia Limousin Rafal Bogacz Bomin Sun Masud Husain Peter Brown Vladimir Litvak |
author_facet |
Ashwini Oswal Chunyan Cao Chien-Hung Yeh Wolf-Julian Neumann James Gratwicke Harith Akram Andreas Horn Dianyou Li Shikun Zhan Chao Zhang Qiang Wang Ludvic Zrinzo Tom Foltynie Patricia Limousin Rafal Bogacz Bomin Sun Masud Husain Peter Brown Vladimir Litvak |
author_sort |
Ashwini Oswal |
title |
Neural signatures of hyperdirect pathway activity in Parkinson’s disease |
title_short |
Neural signatures of hyperdirect pathway activity in Parkinson’s disease |
title_full |
Neural signatures of hyperdirect pathway activity in Parkinson’s disease |
title_fullStr |
Neural signatures of hyperdirect pathway activity in Parkinson’s disease |
title_full_unstemmed |
Neural signatures of hyperdirect pathway activity in Parkinson’s disease |
title_sort |
neural signatures of hyperdirect pathway activity in parkinson’s disease |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/cdfc65b27df649a2be40ee8e183add84 |
work_keys_str_mv |
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