Neural signatures of hyperdirect pathway activity in Parkinson’s disease

In Parkinson’s disease (PD), beta frequency oscillations are synchronised across the cortico-basal-ganglia circuit. The authors show in human participants that high beta frequencies propagate from the cortex to the basal ganglia via the hyperdirect pathway, indicating a pathophysiological role for t...

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Autores principales: Ashwini Oswal, Chunyan Cao, Chien-Hung Yeh, Wolf-Julian Neumann, James Gratwicke, Harith Akram, Andreas Horn, Dianyou Li, Shikun Zhan, Chao Zhang, Qiang Wang, Ludvic Zrinzo, Tom Foltynie, Patricia Limousin, Rafal Bogacz, Bomin Sun, Masud Husain, Peter Brown, Vladimir Litvak
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/cdfc65b27df649a2be40ee8e183add84
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spelling oai:doaj.org-article:cdfc65b27df649a2be40ee8e183add842021-12-02T15:25:36ZNeural signatures of hyperdirect pathway activity in Parkinson’s disease10.1038/s41467-021-25366-02041-1723https://doaj.org/article/cdfc65b27df649a2be40ee8e183add842021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25366-0https://doaj.org/toc/2041-1723In Parkinson’s disease (PD), beta frequency oscillations are synchronised across the cortico-basal-ganglia circuit. The authors show in human participants that high beta frequencies propagate from the cortex to the basal ganglia via the hyperdirect pathway, indicating a pathophysiological role for this pathway in PD.Ashwini OswalChunyan CaoChien-Hung YehWolf-Julian NeumannJames GratwickeHarith AkramAndreas HornDianyou LiShikun ZhanChao ZhangQiang WangLudvic ZrinzoTom FoltyniePatricia LimousinRafal BogaczBomin SunMasud HusainPeter BrownVladimir LitvakNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ashwini Oswal
Chunyan Cao
Chien-Hung Yeh
Wolf-Julian Neumann
James Gratwicke
Harith Akram
Andreas Horn
Dianyou Li
Shikun Zhan
Chao Zhang
Qiang Wang
Ludvic Zrinzo
Tom Foltynie
Patricia Limousin
Rafal Bogacz
Bomin Sun
Masud Husain
Peter Brown
Vladimir Litvak
Neural signatures of hyperdirect pathway activity in Parkinson’s disease
description In Parkinson’s disease (PD), beta frequency oscillations are synchronised across the cortico-basal-ganglia circuit. The authors show in human participants that high beta frequencies propagate from the cortex to the basal ganglia via the hyperdirect pathway, indicating a pathophysiological role for this pathway in PD.
format article
author Ashwini Oswal
Chunyan Cao
Chien-Hung Yeh
Wolf-Julian Neumann
James Gratwicke
Harith Akram
Andreas Horn
Dianyou Li
Shikun Zhan
Chao Zhang
Qiang Wang
Ludvic Zrinzo
Tom Foltynie
Patricia Limousin
Rafal Bogacz
Bomin Sun
Masud Husain
Peter Brown
Vladimir Litvak
author_facet Ashwini Oswal
Chunyan Cao
Chien-Hung Yeh
Wolf-Julian Neumann
James Gratwicke
Harith Akram
Andreas Horn
Dianyou Li
Shikun Zhan
Chao Zhang
Qiang Wang
Ludvic Zrinzo
Tom Foltynie
Patricia Limousin
Rafal Bogacz
Bomin Sun
Masud Husain
Peter Brown
Vladimir Litvak
author_sort Ashwini Oswal
title Neural signatures of hyperdirect pathway activity in Parkinson’s disease
title_short Neural signatures of hyperdirect pathway activity in Parkinson’s disease
title_full Neural signatures of hyperdirect pathway activity in Parkinson’s disease
title_fullStr Neural signatures of hyperdirect pathway activity in Parkinson’s disease
title_full_unstemmed Neural signatures of hyperdirect pathway activity in Parkinson’s disease
title_sort neural signatures of hyperdirect pathway activity in parkinson’s disease
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/cdfc65b27df649a2be40ee8e183add84
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