Quantification of the Elastic Property of Normal Thigh Muscles Using MR Elastography: Our Initial Experience

Purpose This study aimed to apply MR elastography (MRE) to achieve in vivo evaluation of the elastic properties of thigh muscles and validate the feasibility of quantifying the elasticity of normal thigh muscles using MRE. Materials and Methods This prospective study included 10 volunteer subject...

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Autores principales: Junghoon Kim, Jeong Ah Ryu, Juhan Lee
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KO
Publicado: The Korean Society of Radiology 2021
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spelling oai:doaj.org-article:ce001a26c62f4ba9834de17e33aab0762021-11-29T11:12:13ZQuantification of the Elastic Property of Normal Thigh Muscles Using MR Elastography: Our Initial Experience2288-2928https://doaj.org/article/ce001a26c62f4ba9834de17e33aab0762021-11-01T00:00:00Zhttps://doi.org/10.3348/jksr.2020.0133https://doaj.org/toc/2288-2928Purpose This study aimed to apply MR elastography (MRE) to achieve in vivo evaluation of the elastic properties of thigh muscles and validate the feasibility of quantifying the elasticity of normal thigh muscles using MRE. Materials and Methods This prospective study included 10 volunteer subjects [mean age, 32.5 years, (range, 23–45 years)] who reported normal activities of daily living and underwent both T2-weighted axial images and MRE of thigh muscles on the same day. A sequence with a motion- encoding gradient was used in the MRE to map the propagating shear waves in the muscle. Elastic properties were quantified as the shear modulus of the following four thigh muscles at rest; the vastus medialis, vastus lateralis, adductor magnus, and biceps femoris. Results The mean shear modulus was 0.98 ± 0.32 kPa and 1.00 ± 0.33 kPa for the vastus medialis, 1.10 ± 0.46 kPa and 1.07 ± 0.43 kPa for the vastus lateralis, 0.91 ± 0.41 kPa and 0.93 ± 0.47 kPa for the adductor magnus, and 0.99 ± 0.37 kPa and 0.94 ± 0.32 kPa for the biceps femoris, with reader 1 and 2, respectively. No significant difference was observed in the shear modulus based on sex (p < 0.05). Aging consistently showed a statistically significant negative correlation (p < 0.05) with the shear modulus of the thigh muscles, except for the vastus medialis (p = 0.194 for reader 1 and p = 0.355 for reader 2). Conclusion MRE is a quantitative technique used to measure the elastic properties of individual muscles with excellent inter-observer agreement. Age was consistently significantly negatively correlated with the shear stiffness of muscles, except for the vastus medialis.Junghoon KimJeong Ah RyuJuhan LeeThe Korean Society of Radiologyarticlemagnetic resonance imagingmagnetic resonance elastographyelasticity imagingmechanical propertiesskeletal musclethighMedical physics. Medical radiology. Nuclear medicineR895-920ENKO대한영상의학회지, Vol 82, Iss 6, Pp 1556-1564 (2021)
institution DOAJ
collection DOAJ
language EN
KO
topic magnetic resonance imaging
magnetic resonance elastography
elasticity imaging
mechanical properties
skeletal muscle
thigh
Medical physics. Medical radiology. Nuclear medicine
R895-920
spellingShingle magnetic resonance imaging
magnetic resonance elastography
elasticity imaging
mechanical properties
skeletal muscle
thigh
Medical physics. Medical radiology. Nuclear medicine
R895-920
Junghoon Kim
Jeong Ah Ryu
Juhan Lee
Quantification of the Elastic Property of Normal Thigh Muscles Using MR Elastography: Our Initial Experience
description Purpose This study aimed to apply MR elastography (MRE) to achieve in vivo evaluation of the elastic properties of thigh muscles and validate the feasibility of quantifying the elasticity of normal thigh muscles using MRE. Materials and Methods This prospective study included 10 volunteer subjects [mean age, 32.5 years, (range, 23–45 years)] who reported normal activities of daily living and underwent both T2-weighted axial images and MRE of thigh muscles on the same day. A sequence with a motion- encoding gradient was used in the MRE to map the propagating shear waves in the muscle. Elastic properties were quantified as the shear modulus of the following four thigh muscles at rest; the vastus medialis, vastus lateralis, adductor magnus, and biceps femoris. Results The mean shear modulus was 0.98 ± 0.32 kPa and 1.00 ± 0.33 kPa for the vastus medialis, 1.10 ± 0.46 kPa and 1.07 ± 0.43 kPa for the vastus lateralis, 0.91 ± 0.41 kPa and 0.93 ± 0.47 kPa for the adductor magnus, and 0.99 ± 0.37 kPa and 0.94 ± 0.32 kPa for the biceps femoris, with reader 1 and 2, respectively. No significant difference was observed in the shear modulus based on sex (p < 0.05). Aging consistently showed a statistically significant negative correlation (p < 0.05) with the shear modulus of the thigh muscles, except for the vastus medialis (p = 0.194 for reader 1 and p = 0.355 for reader 2). Conclusion MRE is a quantitative technique used to measure the elastic properties of individual muscles with excellent inter-observer agreement. Age was consistently significantly negatively correlated with the shear stiffness of muscles, except for the vastus medialis.
format article
author Junghoon Kim
Jeong Ah Ryu
Juhan Lee
author_facet Junghoon Kim
Jeong Ah Ryu
Juhan Lee
author_sort Junghoon Kim
title Quantification of the Elastic Property of Normal Thigh Muscles Using MR Elastography: Our Initial Experience
title_short Quantification of the Elastic Property of Normal Thigh Muscles Using MR Elastography: Our Initial Experience
title_full Quantification of the Elastic Property of Normal Thigh Muscles Using MR Elastography: Our Initial Experience
title_fullStr Quantification of the Elastic Property of Normal Thigh Muscles Using MR Elastography: Our Initial Experience
title_full_unstemmed Quantification of the Elastic Property of Normal Thigh Muscles Using MR Elastography: Our Initial Experience
title_sort quantification of the elastic property of normal thigh muscles using mr elastography: our initial experience
publisher The Korean Society of Radiology
publishDate 2021
url https://doaj.org/article/ce001a26c62f4ba9834de17e33aab076
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AT jeongahryu quantificationoftheelasticpropertyofnormalthighmusclesusingmrelastographyourinitialexperience
AT juhanlee quantificationoftheelasticpropertyofnormalthighmusclesusingmrelastographyourinitialexperience
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