Metformin promotes innate immunity through a conserved PMK-1/p38 MAPK pathway

Metformin, as the first-line oral drug for type 2 diabetes, has proven benefits against aging, cancer and cardiovascular diseases. But the influence of metformin to the immune response and its molecular mechanisms remain obscure. Metformin increases resistance to not only the Gram-negative pathogens...

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Autores principales: Yi Xiao, Fang Liu, Sanhua Li, Nian Jiang, Changyan Yu, Xinting Zhu, Ying Qin, Jing Hui, Lingjie Meng, Changwei Song, Xiao-Fei Li, Yun Liu
Formato: article
Lenguaje:EN
Publicado: Taylor & Francis Group 2020
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Acceso en línea:https://doaj.org/article/ce01c8a67b434c479938e84cc840fcfc
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