Human Disease Isolates of Serotype M4 and M22 Group A Streptococcus Lack Genes Required for Hyaluronic Acid Capsule Biosynthesis
ABSTRACT Group A streptococcus (GAS) causes human pharyngitis and invasive infections and frequently colonizes individuals asymptomatically. Many lines of evidence generated over decades have shown that the hyaluronic acid capsule is a major virulence factor contributing to these infections. While c...
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Main Authors: | Anthony R. Flores, Brittany E. Jewell, Nahuel Fittipaldi, Stephen B. Beres, James M. Musser |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2012
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Online Access: | https://doaj.org/article/ce0c9c31b7654e03b4e8dfa23cfae2bd |
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