“Neglected nipples”: acanthosis nigricans-like plaques caused by avoidance of nipple cleansing
Background: Acanthosis nigricans (AN) develops sporadically or in association with obesity, insulin-resistance and dark pigmentary phenotype. Unusual clinical presentations of AN may be diagnostically vexing. Objectives: The aim of the report is to present unusual clinical and dermoscopic pictur...
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| Autores principales: | , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Mattioli1885
2014
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/ce0e400619574ba6a5af2ae79884ec2d |
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| Sumario: | Background: Acanthosis nigricans (AN) develops sporadically or in association with obesity, insulin-resistance and dark pigmentary phenotype. Unusual clinical presentations of AN may be diagnostically vexing.
Objectives: The aim of the report is to present unusual clinical and dermoscopic pictures of hyperkeratotic, brownish lesions of the nipples resembling acanthosis nigricans.
Patients/Methods: Data including clinical and dermoscopic features of two patients with the “neglected nipples”: acanthosis nigricans-like (AN-like) hyperpigmented plaques caused by avoidance of nipple cleansing.
Results: Beside the anamnestic clue, presentation of AN-like plaques in the “neglected nipples” is limited to the breasts, in the absence of involvement of other flexural sites classically affected by AN.Dermoscopy aids the exclusion of a tumor, as it reveals exclusively structureless, brown-gray-black hyperkeratosis in the absence of criteria associated with melanocytic or non-melanocytic skin neoplasms of the nipple. The “neglected breasts” are easily treated by keratolytic creams and hygiene.
Conclusions: The “neglected nipples” condition, presenting as bilateral AN-like papules and plaques of the nipples, is due to avoidance of cleansing of the nipple area, resulting in accumulation of keratotic cellular debris.
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