The use of reflectance confocal microscopy for monitoring response to therapy of skin malignancies

Reflectance confocal microscopy (RCM) is a new non-invasive imaging technique that enables visualizing cells and structures in living skin in real-time with resolution close to that of histological analysis. RCM has been successfully implemented in the assessment of benign and malignant lesions. Mo...

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Main Authors:	Marina Ulrich, Susanne Lange-Asschenfeldt, Salvador Gonzalez
Format:	article
Language:	EN
Published:	Mattioli1885 2012
Subjects:	reflectance confocal microscopy dermatoscopy Dermatology RL1-803
Online Access:	https://doaj.org/article/ce19d1ab657d45bbb221bfa4ef4d9670
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spelling	oai:doaj.org-article:ce19d1ab657d45bbb221bfa4ef4d96702021-11-17T08:33:09ZThe use of reflectance confocal microscopy for monitoring response to therapy of skin malignancies10.5826/dpc.0202a102160-9381https://doaj.org/article/ce19d1ab657d45bbb221bfa4ef4d96702012-04-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/1171https://doaj.org/toc/2160-9381 Reflectance confocal microscopy (RCM) is a new non-invasive imaging technique that enables visualizing cells and structures in living skin in real-time with resolution close to that of histological analysis. RCM has been successfully implemented in the assessment of benign and malignant lesions. Most importantly, it also enables monitoring dynamic changes in the skin over time and in response to different therapies, e.g., imiquimod, photodynamic therapy, and others. Given the often traumatic nature of skin cancer that affects both the physiology and the psychology of the patients, it is crucial to have methods that enable monitoring the response to treatment but that minimize the distress and discomfort associated with such process. This article provides a very brief overview of the fundamentals of RCM and then focuses on its recent employment as a monitoring tool in skin cancer and other pathologies that may require frequent follow-up. Marina UlrichSusanne Lange-AsschenfeldtSalvador GonzalezMattioli1885articlereflectance confocal microscopydermatoscopyDermatologyRL1-803ENDermatology Practical & Conceptual (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	reflectance confocal microscopy dermatoscopy Dermatology RL1-803
spellingShingle	reflectance confocal microscopy dermatoscopy Dermatology RL1-803 Marina Ulrich Susanne Lange-Asschenfeldt Salvador Gonzalez The use of reflectance confocal microscopy for monitoring response to therapy of skin malignancies
description	Reflectance confocal microscopy (RCM) is a new non-invasive imaging technique that enables visualizing cells and structures in living skin in real-time with resolution close to that of histological analysis. RCM has been successfully implemented in the assessment of benign and malignant lesions. Most importantly, it also enables monitoring dynamic changes in the skin over time and in response to different therapies, e.g., imiquimod, photodynamic therapy, and others. Given the often traumatic nature of skin cancer that affects both the physiology and the psychology of the patients, it is crucial to have methods that enable monitoring the response to treatment but that minimize the distress and discomfort associated with such process. This article provides a very brief overview of the fundamentals of RCM and then focuses on its recent employment as a monitoring tool in skin cancer and other pathologies that may require frequent follow-up.
format	article
author	Marina Ulrich Susanne Lange-Asschenfeldt Salvador Gonzalez
author_facet	Marina Ulrich Susanne Lange-Asschenfeldt Salvador Gonzalez
author_sort	Marina Ulrich
title	The use of reflectance confocal microscopy for monitoring response to therapy of skin malignancies
title_short	The use of reflectance confocal microscopy for monitoring response to therapy of skin malignancies
title_full	The use of reflectance confocal microscopy for monitoring response to therapy of skin malignancies
title_fullStr	The use of reflectance confocal microscopy for monitoring response to therapy of skin malignancies
title_full_unstemmed	The use of reflectance confocal microscopy for monitoring response to therapy of skin malignancies
title_sort	use of reflectance confocal microscopy for monitoring response to therapy of skin malignancies
publisher	Mattioli1885
publishDate	2012
url	https://doaj.org/article/ce19d1ab657d45bbb221bfa4ef4d9670
work_keys_str_mv	AT marinaulrich theuseofreflectanceconfocalmicroscopyformonitoringresponsetotherapyofskinmalignancies AT susannelangeasschenfeldt theuseofreflectanceconfocalmicroscopyformonitoringresponsetotherapyofskinmalignancies AT salvadorgonzalez theuseofreflectanceconfocalmicroscopyformonitoringresponsetotherapyofskinmalignancies AT marinaulrich useofreflectanceconfocalmicroscopyformonitoringresponsetotherapyofskinmalignancies AT susannelangeasschenfeldt useofreflectanceconfocalmicroscopyformonitoringresponsetotherapyofskinmalignancies AT salvadorgonzalez useofreflectanceconfocalmicroscopyformonitoringresponsetotherapyofskinmalignancies
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The use of reflectance confocal microscopy for monitoring response to therapy of skin malignancies

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