The use of reflectance confocal microscopy for monitoring response to therapy of skin malignancies
Reflectance confocal microscopy (RCM) is a new non-invasive imaging technique that enables visualizing cells and structures in living skin in real-time with resolution close to that of histological analysis. RCM has been successfully implemented in the assessment of benign and malignant lesions. Mo...
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Mattioli1885
2012
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oai:doaj.org-article:ce19d1ab657d45bbb221bfa4ef4d96702021-11-17T08:33:09ZThe use of reflectance confocal microscopy for monitoring response to therapy of skin malignancies10.5826/dpc.0202a102160-9381https://doaj.org/article/ce19d1ab657d45bbb221bfa4ef4d96702012-04-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/1171https://doaj.org/toc/2160-9381 Reflectance confocal microscopy (RCM) is a new non-invasive imaging technique that enables visualizing cells and structures in living skin in real-time with resolution close to that of histological analysis. RCM has been successfully implemented in the assessment of benign and malignant lesions. Most importantly, it also enables monitoring dynamic changes in the skin over time and in response to different therapies, e.g., imiquimod, photodynamic therapy, and others. Given the often traumatic nature of skin cancer that affects both the physiology and the psychology of the patients, it is crucial to have methods that enable monitoring the response to treatment but that minimize the distress and discomfort associated with such process. This article provides a very brief overview of the fundamentals of RCM and then focuses on its recent employment as a monitoring tool in skin cancer and other pathologies that may require frequent follow-up. Marina UlrichSusanne Lange-AsschenfeldtSalvador GonzalezMattioli1885articlereflectance confocal microscopydermatoscopyDermatologyRL1-803ENDermatology Practical & Conceptual (2012) |
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reflectance confocal microscopy dermatoscopy Dermatology RL1-803 |
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reflectance confocal microscopy dermatoscopy Dermatology RL1-803 Marina Ulrich Susanne Lange-Asschenfeldt Salvador Gonzalez The use of reflectance confocal microscopy for monitoring response to therapy of skin malignancies |
description |
Reflectance confocal microscopy (RCM) is a new non-invasive imaging technique that enables visualizing cells and structures in living skin in real-time with resolution close to that of histological analysis. RCM has been successfully implemented in the assessment of benign and malignant lesions. Most importantly, it also enables monitoring dynamic changes in the skin over time and in response to different therapies, e.g., imiquimod, photodynamic therapy, and others. Given the often traumatic nature of skin cancer that affects both the physiology and the psychology of the patients, it is crucial to have methods that enable monitoring the response to treatment but that minimize the distress and discomfort associated with such process. This article provides a very brief overview of the fundamentals of RCM and then focuses on its recent employment as a monitoring tool in skin cancer and other pathologies that may require frequent follow-up.
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format |
article |
author |
Marina Ulrich Susanne Lange-Asschenfeldt Salvador Gonzalez |
author_facet |
Marina Ulrich Susanne Lange-Asschenfeldt Salvador Gonzalez |
author_sort |
Marina Ulrich |
title |
The use of reflectance confocal microscopy for monitoring response to therapy of skin malignancies |
title_short |
The use of reflectance confocal microscopy for monitoring response to therapy of skin malignancies |
title_full |
The use of reflectance confocal microscopy for monitoring response to therapy of skin malignancies |
title_fullStr |
The use of reflectance confocal microscopy for monitoring response to therapy of skin malignancies |
title_full_unstemmed |
The use of reflectance confocal microscopy for monitoring response to therapy of skin malignancies |
title_sort |
use of reflectance confocal microscopy for monitoring response to therapy of skin malignancies |
publisher |
Mattioli1885 |
publishDate |
2012 |
url |
https://doaj.org/article/ce19d1ab657d45bbb221bfa4ef4d9670 |
work_keys_str_mv |
AT marinaulrich theuseofreflectanceconfocalmicroscopyformonitoringresponsetotherapyofskinmalignancies AT susannelangeasschenfeldt theuseofreflectanceconfocalmicroscopyformonitoringresponsetotherapyofskinmalignancies AT salvadorgonzalez theuseofreflectanceconfocalmicroscopyformonitoringresponsetotherapyofskinmalignancies AT marinaulrich useofreflectanceconfocalmicroscopyformonitoringresponsetotherapyofskinmalignancies AT susannelangeasschenfeldt useofreflectanceconfocalmicroscopyformonitoringresponsetotherapyofskinmalignancies AT salvadorgonzalez useofreflectanceconfocalmicroscopyformonitoringresponsetotherapyofskinmalignancies |
_version_ |
1718425701184438272 |