Identification of a prefrontal cortex-to-amygdala pathway for chronic stress-induced anxiety
Dysregulated prefrontal control over amygdala has been implicated in the etiology of stress-related psychiatric disorders. Here, the authors show that the dysregulation preferentially occurs in amygdala neurons that are mono- but not bi-directionally connected with dorsomedial prefrontal cortex.
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Nature Portfolio
2020
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oai:doaj.org-article:ce1defeaf51f4f219db265206bb791252021-12-02T14:40:50ZIdentification of a prefrontal cortex-to-amygdala pathway for chronic stress-induced anxiety10.1038/s41467-020-15920-72041-1723https://doaj.org/article/ce1defeaf51f4f219db265206bb791252020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15920-7https://doaj.org/toc/2041-1723Dysregulated prefrontal control over amygdala has been implicated in the etiology of stress-related psychiatric disorders. Here, the authors show that the dysregulation preferentially occurs in amygdala neurons that are mono- but not bi-directionally connected with dorsomedial prefrontal cortex.Wei-Zhu LiuWen-Hua ZhangZhi-Heng ZhengJia-Xin ZouXiao-Xuan LiuShou-He HuangWen-Jie YouYe HeJun-Yu ZhangXiao-Dong WangBing-Xing PanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020) |
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DOAJ |
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EN |
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Science Q Wei-Zhu Liu Wen-Hua Zhang Zhi-Heng Zheng Jia-Xin Zou Xiao-Xuan Liu Shou-He Huang Wen-Jie You Ye He Jun-Yu Zhang Xiao-Dong Wang Bing-Xing Pan Identification of a prefrontal cortex-to-amygdala pathway for chronic stress-induced anxiety |
description |
Dysregulated prefrontal control over amygdala has been implicated in the etiology of stress-related psychiatric disorders. Here, the authors show that the dysregulation preferentially occurs in amygdala neurons that are mono- but not bi-directionally connected with dorsomedial prefrontal cortex. |
format |
article |
author |
Wei-Zhu Liu Wen-Hua Zhang Zhi-Heng Zheng Jia-Xin Zou Xiao-Xuan Liu Shou-He Huang Wen-Jie You Ye He Jun-Yu Zhang Xiao-Dong Wang Bing-Xing Pan |
author_facet |
Wei-Zhu Liu Wen-Hua Zhang Zhi-Heng Zheng Jia-Xin Zou Xiao-Xuan Liu Shou-He Huang Wen-Jie You Ye He Jun-Yu Zhang Xiao-Dong Wang Bing-Xing Pan |
author_sort |
Wei-Zhu Liu |
title |
Identification of a prefrontal cortex-to-amygdala pathway for chronic stress-induced anxiety |
title_short |
Identification of a prefrontal cortex-to-amygdala pathway for chronic stress-induced anxiety |
title_full |
Identification of a prefrontal cortex-to-amygdala pathway for chronic stress-induced anxiety |
title_fullStr |
Identification of a prefrontal cortex-to-amygdala pathway for chronic stress-induced anxiety |
title_full_unstemmed |
Identification of a prefrontal cortex-to-amygdala pathway for chronic stress-induced anxiety |
title_sort |
identification of a prefrontal cortex-to-amygdala pathway for chronic stress-induced anxiety |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/ce1defeaf51f4f219db265206bb79125 |
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