Identification of a prefrontal cortex-to-amygdala pathway for chronic stress-induced anxiety

Dysregulated prefrontal control over amygdala has been implicated in the etiology of stress-related psychiatric disorders. Here, the authors show that the dysregulation preferentially occurs in amygdala neurons that are mono- but not bi-directionally connected with dorsomedial prefrontal cortex.

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Autores principales: Wei-Zhu Liu, Wen-Hua Zhang, Zhi-Heng Zheng, Jia-Xin Zou, Xiao-Xuan Liu, Shou-He Huang, Wen-Jie You, Ye He, Jun-Yu Zhang, Xiao-Dong Wang, Bing-Xing Pan
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/ce1defeaf51f4f219db265206bb79125
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spelling oai:doaj.org-article:ce1defeaf51f4f219db265206bb791252021-12-02T14:40:50ZIdentification of a prefrontal cortex-to-amygdala pathway for chronic stress-induced anxiety10.1038/s41467-020-15920-72041-1723https://doaj.org/article/ce1defeaf51f4f219db265206bb791252020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15920-7https://doaj.org/toc/2041-1723Dysregulated prefrontal control over amygdala has been implicated in the etiology of stress-related psychiatric disorders. Here, the authors show that the dysregulation preferentially occurs in amygdala neurons that are mono- but not bi-directionally connected with dorsomedial prefrontal cortex.Wei-Zhu LiuWen-Hua ZhangZhi-Heng ZhengJia-Xin ZouXiao-Xuan LiuShou-He HuangWen-Jie YouYe HeJun-Yu ZhangXiao-Dong WangBing-Xing PanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Wei-Zhu Liu
Wen-Hua Zhang
Zhi-Heng Zheng
Jia-Xin Zou
Xiao-Xuan Liu
Shou-He Huang
Wen-Jie You
Ye He
Jun-Yu Zhang
Xiao-Dong Wang
Bing-Xing Pan
Identification of a prefrontal cortex-to-amygdala pathway for chronic stress-induced anxiety
description Dysregulated prefrontal control over amygdala has been implicated in the etiology of stress-related psychiatric disorders. Here, the authors show that the dysregulation preferentially occurs in amygdala neurons that are mono- but not bi-directionally connected with dorsomedial prefrontal cortex.
format article
author Wei-Zhu Liu
Wen-Hua Zhang
Zhi-Heng Zheng
Jia-Xin Zou
Xiao-Xuan Liu
Shou-He Huang
Wen-Jie You
Ye He
Jun-Yu Zhang
Xiao-Dong Wang
Bing-Xing Pan
author_facet Wei-Zhu Liu
Wen-Hua Zhang
Zhi-Heng Zheng
Jia-Xin Zou
Xiao-Xuan Liu
Shou-He Huang
Wen-Jie You
Ye He
Jun-Yu Zhang
Xiao-Dong Wang
Bing-Xing Pan
author_sort Wei-Zhu Liu
title Identification of a prefrontal cortex-to-amygdala pathway for chronic stress-induced anxiety
title_short Identification of a prefrontal cortex-to-amygdala pathway for chronic stress-induced anxiety
title_full Identification of a prefrontal cortex-to-amygdala pathway for chronic stress-induced anxiety
title_fullStr Identification of a prefrontal cortex-to-amygdala pathway for chronic stress-induced anxiety
title_full_unstemmed Identification of a prefrontal cortex-to-amygdala pathway for chronic stress-induced anxiety
title_sort identification of a prefrontal cortex-to-amygdala pathway for chronic stress-induced anxiety
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/ce1defeaf51f4f219db265206bb79125
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