Sustained micellar delivery via inducible transitions in nanostructure morphology

Nanocarrier administration is often performed via intermittent bolus injection while sustained delivery platforms are rarely reported. Here the authors demonstrate that the cylinder-to-sphere transitions of self-assembled filomicelle scaffolds can be used for sustained delivery with improved resorpt...

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Autores principales: Nicholas B. Karabin, Sean Allen, Ha-Kyung Kwon, Sharan Bobbala, Emre Firlar, Tolou Shokuhfar, Kenneth R. Shull, Evan A. Scott
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/ce2bb2bc8ef841a2af53aed925aacee2
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spelling oai:doaj.org-article:ce2bb2bc8ef841a2af53aed925aacee22021-12-02T15:34:42ZSustained micellar delivery via inducible transitions in nanostructure morphology10.1038/s41467-018-03001-92041-1723https://doaj.org/article/ce2bb2bc8ef841a2af53aed925aacee22018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03001-9https://doaj.org/toc/2041-1723Nanocarrier administration is often performed via intermittent bolus injection while sustained delivery platforms are rarely reported. Here the authors demonstrate that the cylinder-to-sphere transitions of self-assembled filomicelle scaffolds can be used for sustained delivery with improved resorptive capacity and biocompatibility.Nicholas B. KarabinSean AllenHa-Kyung KwonSharan BobbalaEmre FirlarTolou ShokuhfarKenneth R. ShullEvan A. ScottNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Nicholas B. Karabin
Sean Allen
Ha-Kyung Kwon
Sharan Bobbala
Emre Firlar
Tolou Shokuhfar
Kenneth R. Shull
Evan A. Scott
Sustained micellar delivery via inducible transitions in nanostructure morphology
description Nanocarrier administration is often performed via intermittent bolus injection while sustained delivery platforms are rarely reported. Here the authors demonstrate that the cylinder-to-sphere transitions of self-assembled filomicelle scaffolds can be used for sustained delivery with improved resorptive capacity and biocompatibility.
format article
author Nicholas B. Karabin
Sean Allen
Ha-Kyung Kwon
Sharan Bobbala
Emre Firlar
Tolou Shokuhfar
Kenneth R. Shull
Evan A. Scott
author_facet Nicholas B. Karabin
Sean Allen
Ha-Kyung Kwon
Sharan Bobbala
Emre Firlar
Tolou Shokuhfar
Kenneth R. Shull
Evan A. Scott
author_sort Nicholas B. Karabin
title Sustained micellar delivery via inducible transitions in nanostructure morphology
title_short Sustained micellar delivery via inducible transitions in nanostructure morphology
title_full Sustained micellar delivery via inducible transitions in nanostructure morphology
title_fullStr Sustained micellar delivery via inducible transitions in nanostructure morphology
title_full_unstemmed Sustained micellar delivery via inducible transitions in nanostructure morphology
title_sort sustained micellar delivery via inducible transitions in nanostructure morphology
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/ce2bb2bc8ef841a2af53aed925aacee2
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