Sustained micellar delivery via inducible transitions in nanostructure morphology
Nanocarrier administration is often performed via intermittent bolus injection while sustained delivery platforms are rarely reported. Here the authors demonstrate that the cylinder-to-sphere transitions of self-assembled filomicelle scaffolds can be used for sustained delivery with improved resorpt...
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oai:doaj.org-article:ce2bb2bc8ef841a2af53aed925aacee22021-12-02T15:34:42ZSustained micellar delivery via inducible transitions in nanostructure morphology10.1038/s41467-018-03001-92041-1723https://doaj.org/article/ce2bb2bc8ef841a2af53aed925aacee22018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03001-9https://doaj.org/toc/2041-1723Nanocarrier administration is often performed via intermittent bolus injection while sustained delivery platforms are rarely reported. Here the authors demonstrate that the cylinder-to-sphere transitions of self-assembled filomicelle scaffolds can be used for sustained delivery with improved resorptive capacity and biocompatibility.Nicholas B. KarabinSean AllenHa-Kyung KwonSharan BobbalaEmre FirlarTolou ShokuhfarKenneth R. ShullEvan A. ScottNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018) |
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Science Q Nicholas B. Karabin Sean Allen Ha-Kyung Kwon Sharan Bobbala Emre Firlar Tolou Shokuhfar Kenneth R. Shull Evan A. Scott Sustained micellar delivery via inducible transitions in nanostructure morphology |
description |
Nanocarrier administration is often performed via intermittent bolus injection while sustained delivery platforms are rarely reported. Here the authors demonstrate that the cylinder-to-sphere transitions of self-assembled filomicelle scaffolds can be used for sustained delivery with improved resorptive capacity and biocompatibility. |
format |
article |
author |
Nicholas B. Karabin Sean Allen Ha-Kyung Kwon Sharan Bobbala Emre Firlar Tolou Shokuhfar Kenneth R. Shull Evan A. Scott |
author_facet |
Nicholas B. Karabin Sean Allen Ha-Kyung Kwon Sharan Bobbala Emre Firlar Tolou Shokuhfar Kenneth R. Shull Evan A. Scott |
author_sort |
Nicholas B. Karabin |
title |
Sustained micellar delivery via inducible transitions in nanostructure morphology |
title_short |
Sustained micellar delivery via inducible transitions in nanostructure morphology |
title_full |
Sustained micellar delivery via inducible transitions in nanostructure morphology |
title_fullStr |
Sustained micellar delivery via inducible transitions in nanostructure morphology |
title_full_unstemmed |
Sustained micellar delivery via inducible transitions in nanostructure morphology |
title_sort |
sustained micellar delivery via inducible transitions in nanostructure morphology |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/ce2bb2bc8ef841a2af53aed925aacee2 |
work_keys_str_mv |
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1718386807927734272 |