Coordinated force generation of skeletal myosins in myofilaments through motor coupling

Skeletal muscle myosin forms large ensembles to generate force against high loads. Using optical tweezers and simulation Kayaet al. provide experimental evidence for cooperative force generation, and describe how the molecular properties of skeletal myosins are tuned for coordinated power strokes.

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Autores principales:	Motoshi Kaya, Yoshiaki Tani, Takumi Washio, Toshiaki Hisada, Hideo Higuchi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ce3987606aff4fb0bbb5abd6897b3bf8
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spelling	oai:doaj.org-article:ce3987606aff4fb0bbb5abd6897b3bf82021-12-02T14:40:23ZCoordinated force generation of skeletal myosins in myofilaments through motor coupling10.1038/ncomms160362041-1723https://doaj.org/article/ce3987606aff4fb0bbb5abd6897b3bf82017-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms16036https://doaj.org/toc/2041-1723Skeletal muscle myosin forms large ensembles to generate force against high loads. Using optical tweezers and simulation Kayaet al. provide experimental evidence for cooperative force generation, and describe how the molecular properties of skeletal myosins are tuned for coordinated power strokes.Motoshi KayaYoshiaki TaniTakumi WashioToshiaki HisadaHideo HiguchiNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Motoshi Kaya Yoshiaki Tani Takumi Washio Toshiaki Hisada Hideo Higuchi Coordinated force generation of skeletal myosins in myofilaments through motor coupling
description	Skeletal muscle myosin forms large ensembles to generate force against high loads. Using optical tweezers and simulation Kayaet al. provide experimental evidence for cooperative force generation, and describe how the molecular properties of skeletal myosins are tuned for coordinated power strokes.
format	article
author	Motoshi Kaya Yoshiaki Tani Takumi Washio Toshiaki Hisada Hideo Higuchi
author_facet	Motoshi Kaya Yoshiaki Tani Takumi Washio Toshiaki Hisada Hideo Higuchi
author_sort	Motoshi Kaya
title	Coordinated force generation of skeletal myosins in myofilaments through motor coupling
title_short	Coordinated force generation of skeletal myosins in myofilaments through motor coupling
title_full	Coordinated force generation of skeletal myosins in myofilaments through motor coupling
title_fullStr	Coordinated force generation of skeletal myosins in myofilaments through motor coupling
title_full_unstemmed	Coordinated force generation of skeletal myosins in myofilaments through motor coupling
title_sort	coordinated force generation of skeletal myosins in myofilaments through motor coupling
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/ce3987606aff4fb0bbb5abd6897b3bf8
work_keys_str_mv	AT motoshikaya coordinatedforcegenerationofskeletalmyosinsinmyofilamentsthroughmotorcoupling AT yoshiakitani coordinatedforcegenerationofskeletalmyosinsinmyofilamentsthroughmotorcoupling AT takumiwashio coordinatedforcegenerationofskeletalmyosinsinmyofilamentsthroughmotorcoupling AT toshiakihisada coordinatedforcegenerationofskeletalmyosinsinmyofilamentsthroughmotorcoupling AT hideohiguchi coordinatedforcegenerationofskeletalmyosinsinmyofilamentsthroughmotorcoupling
_version_	1718390324707983360

Coordinated force generation of skeletal myosins in myofilaments through motor coupling

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