Herpes simplex virus 1 targets IRF7 via ICP0 to limit type I IFN induction

Herpes simplex virus 1 targets IRF7 via ICP0 to limit type I IFN induction

Abstract Herpes simplex keratitis (HSK), caused by herpes simplex virus type 1 (HSV-1) infection, is the commonest cause of infectious blindness in the developed world. Following infection the virus is initially suspended in the tear film, where it encounters a multi-pronged immune response comprisi...

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Autores principales: David Shahnazaryan, Rana Khalil, Claire Wynne, Caroline A. Jefferies, Joan Ní Gabhann-Dromgoole, Conor C. Murphy
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/ce3c1ce58bd24780879b3e7ca5fe90f2
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