Unsaturated fatty acid salts remove biofilms on dentures

Abstract Candidiasis-causing Candida sp. forms biofilms with various oral bacteria in the dentures of the elderly, making it harder to kill and remove the microorganism due to the extracellular polymeric substances. We found that biofilms on dentures can effectively be removed by immersion in an uns...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Teruyuki Hara, Atsunori Sonoi, Takuya Handa, Masayuki Okamoto, Eri Kaneko, Reiko Ikeda, Taichi Habe, Hidetake Fujinaka, Shigeto Inoue, Tetsuo Ichikawa
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/ce3fdfcb442d4d638fbf2007aa7fc93f
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:ce3fdfcb442d4d638fbf2007aa7fc93f
record_format	dspace
spelling	oai:doaj.org-article:ce3fdfcb442d4d638fbf2007aa7fc93f2021-12-02T17:23:49ZUnsaturated fatty acid salts remove biofilms on dentures10.1038/s41598-021-92044-y2045-2322https://doaj.org/article/ce3fdfcb442d4d638fbf2007aa7fc93f2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-92044-yhttps://doaj.org/toc/2045-2322Abstract Candidiasis-causing Candida sp. forms biofilms with various oral bacteria in the dentures of the elderly, making it harder to kill and remove the microorganism due to the extracellular polymeric substances. We found that biofilms on dentures can effectively be removed by immersion in an unsaturated fatty acid salt solution. Using optical coherence tomography to observe the progression of biofilm removal by the fatty acid salt solution, we were able to determine that the removal was accompanied by the production of gaps at the interface between the biofilm and denture resin. Furthermore, microstructural electron microscopy observations and time-of-flight secondary ion mass spectrometry elucidated the site of action, revealing that localization of the fatty acid salt at the biofilm/denture-resin interface is an important factor.Teruyuki HaraAtsunori SonoiTakuya HandaMasayuki OkamotoEri KanekoReiko IkedaTaichi HabeHidetake FujinakaShigeto InoueTetsuo IchikawaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Teruyuki Hara Atsunori Sonoi Takuya Handa Masayuki Okamoto Eri Kaneko Reiko Ikeda Taichi Habe Hidetake Fujinaka Shigeto Inoue Tetsuo Ichikawa Unsaturated fatty acid salts remove biofilms on dentures
description	Abstract Candidiasis-causing Candida sp. forms biofilms with various oral bacteria in the dentures of the elderly, making it harder to kill and remove the microorganism due to the extracellular polymeric substances. We found that biofilms on dentures can effectively be removed by immersion in an unsaturated fatty acid salt solution. Using optical coherence tomography to observe the progression of biofilm removal by the fatty acid salt solution, we were able to determine that the removal was accompanied by the production of gaps at the interface between the biofilm and denture resin. Furthermore, microstructural electron microscopy observations and time-of-flight secondary ion mass spectrometry elucidated the site of action, revealing that localization of the fatty acid salt at the biofilm/denture-resin interface is an important factor.
format	article
author	Teruyuki Hara Atsunori Sonoi Takuya Handa Masayuki Okamoto Eri Kaneko Reiko Ikeda Taichi Habe Hidetake Fujinaka Shigeto Inoue Tetsuo Ichikawa
author_facet	Teruyuki Hara Atsunori Sonoi Takuya Handa Masayuki Okamoto Eri Kaneko Reiko Ikeda Taichi Habe Hidetake Fujinaka Shigeto Inoue Tetsuo Ichikawa
author_sort	Teruyuki Hara
title	Unsaturated fatty acid salts remove biofilms on dentures
title_short	Unsaturated fatty acid salts remove biofilms on dentures
title_full	Unsaturated fatty acid salts remove biofilms on dentures
title_fullStr	Unsaturated fatty acid salts remove biofilms on dentures
title_full_unstemmed	Unsaturated fatty acid salts remove biofilms on dentures
title_sort	unsaturated fatty acid salts remove biofilms on dentures
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/ce3fdfcb442d4d638fbf2007aa7fc93f
work_keys_str_mv	AT teruyukihara unsaturatedfattyacidsaltsremovebiofilmsondentures AT atsunorisonoi unsaturatedfattyacidsaltsremovebiofilmsondentures AT takuyahanda unsaturatedfattyacidsaltsremovebiofilmsondentures AT masayukiokamoto unsaturatedfattyacidsaltsremovebiofilmsondentures AT erikaneko unsaturatedfattyacidsaltsremovebiofilmsondentures AT reikoikeda unsaturatedfattyacidsaltsremovebiofilmsondentures AT taichihabe unsaturatedfattyacidsaltsremovebiofilmsondentures AT hidetakefujinaka unsaturatedfattyacidsaltsremovebiofilmsondentures AT shigetoinoue unsaturatedfattyacidsaltsremovebiofilmsondentures AT tetsuoichikawa unsaturatedfattyacidsaltsremovebiofilmsondentures
_version_	1718380995755900928

Unsaturated fatty acid salts remove biofilms on dentures

Ejemplares similares