MTHFD1 controls DNA methylation in Arabidopsis

DNA methylation contributes to transcriptional silencing. Here, Groth et al.show that mutant plants defective in MTHFD1, an enzyme involved in folate metabolism, have a DNA hypomethylation phenotype highlighting the link between one-carbon metabolism and DNA methylation, which is mediated by SAM as...

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Autores principales:	Martin Groth, Guillaume Moissiard, Markus Wirtz, Haifeng Wang, Carolina Garcia-Salinas, Perla A. Ramos-Parra, Sylvain Bischof, Suhua Feng, Shawn J. Cokus, Amala John, Danielle C. Smith, Jixian Zhai, Christopher J. Hale, Jeff A. Long, Ruediger Hell, Rocío I. Díaz de la Garza, Steven E. Jacobsen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ce40b8d8684f4a36a5143251814e191e
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spelling	oai:doaj.org-article:ce40b8d8684f4a36a5143251814e191e2021-12-02T15:35:44ZMTHFD1 controls DNA methylation in Arabidopsis10.1038/ncomms116402041-1723https://doaj.org/article/ce40b8d8684f4a36a5143251814e191e2016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11640https://doaj.org/toc/2041-1723DNA methylation contributes to transcriptional silencing. Here, Groth et al.show that mutant plants defective in MTHFD1, an enzyme involved in folate metabolism, have a DNA hypomethylation phenotype highlighting the link between one-carbon metabolism and DNA methylation, which is mediated by SAM as a common methyl donor.Martin GrothGuillaume MoissiardMarkus WirtzHaifeng WangCarolina Garcia-SalinasPerla A. Ramos-ParraSylvain BischofSuhua FengShawn J. CokusAmala JohnDanielle C. SmithJixian ZhaiChristopher J. HaleJeff A. LongRuediger HellRocío I. Díaz de la GarzaSteven E. JacobsenNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Martin Groth Guillaume Moissiard Markus Wirtz Haifeng Wang Carolina Garcia-Salinas Perla A. Ramos-Parra Sylvain Bischof Suhua Feng Shawn J. Cokus Amala John Danielle C. Smith Jixian Zhai Christopher J. Hale Jeff A. Long Ruediger Hell Rocío I. Díaz de la Garza Steven E. Jacobsen MTHFD1 controls DNA methylation in Arabidopsis
description	DNA methylation contributes to transcriptional silencing. Here, Groth et al.show that mutant plants defective in MTHFD1, an enzyme involved in folate metabolism, have a DNA hypomethylation phenotype highlighting the link between one-carbon metabolism and DNA methylation, which is mediated by SAM as a common methyl donor.
format	article
author	Martin Groth Guillaume Moissiard Markus Wirtz Haifeng Wang Carolina Garcia-Salinas Perla A. Ramos-Parra Sylvain Bischof Suhua Feng Shawn J. Cokus Amala John Danielle C. Smith Jixian Zhai Christopher J. Hale Jeff A. Long Ruediger Hell Rocío I. Díaz de la Garza Steven E. Jacobsen
author_facet	Martin Groth Guillaume Moissiard Markus Wirtz Haifeng Wang Carolina Garcia-Salinas Perla A. Ramos-Parra Sylvain Bischof Suhua Feng Shawn J. Cokus Amala John Danielle C. Smith Jixian Zhai Christopher J. Hale Jeff A. Long Ruediger Hell Rocío I. Díaz de la Garza Steven E. Jacobsen
author_sort	Martin Groth
title	MTHFD1 controls DNA methylation in Arabidopsis
title_short	MTHFD1 controls DNA methylation in Arabidopsis
title_full	MTHFD1 controls DNA methylation in Arabidopsis
title_fullStr	MTHFD1 controls DNA methylation in Arabidopsis
title_full_unstemmed	MTHFD1 controls DNA methylation in Arabidopsis
title_sort	mthfd1 controls dna methylation in arabidopsis
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/ce40b8d8684f4a36a5143251814e191e
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MTHFD1 controls DNA methylation in Arabidopsis

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