Plasma cell differentiation is controlled by multiple cell division-coupled epigenetic programs

During B cell differentiation, the role of different genomic loci in transcriptional and epigenetic regulation in vivo is not well defined. Here the authors use an in vivo B cell differentiation model to map cellular division-dependent cis-regulatory element road map with ATAC-seq.

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Detalles Bibliográficos
Autores principales: Christopher D. Scharer, Benjamin G. Barwick, Muyao Guo, Alexander P. R. Bally, Jeremy M. Boss
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/ce454525ef924494b954d29152418aee
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Descripción
Sumario:During B cell differentiation, the role of different genomic loci in transcriptional and epigenetic regulation in vivo is not well defined. Here the authors use an in vivo B cell differentiation model to map cellular division-dependent cis-regulatory element road map with ATAC-seq.