The machinery underlying malaria parasite virulence is conserved between rodent and human malaria parasites

Proteins SBP1 and MAHRP1 of the human malaria parasite are required for sequestration of infected red blood cells in major organs. Here, De Niz et al. identify homologous proteins in the rodent parasite Plasmodium berghei, showing that they play similar roles and supporting the usefulness of malaria...

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Autores principales: Mariana De Niz, Ann-Katrin Ullrich, Arlett Heiber, Alexandra Blancke Soares, Christian Pick, Ruth Lyck, Derya Keller, Gesine Kaiser, Monica Prado, Sven Flemming, Hernando del Portillo, Chris J. Janse, Volker Heussler, Tobias Spielmann
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Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/ce5dde75c34e4b5ebcf04a7b660268c8
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spelling oai:doaj.org-article:ce5dde75c34e4b5ebcf04a7b660268c82021-12-02T14:39:13ZThe machinery underlying malaria parasite virulence is conserved between rodent and human malaria parasites10.1038/ncomms116592041-1723https://doaj.org/article/ce5dde75c34e4b5ebcf04a7b660268c82016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11659https://doaj.org/toc/2041-1723Proteins SBP1 and MAHRP1 of the human malaria parasite are required for sequestration of infected red blood cells in major organs. Here, De Niz et al. identify homologous proteins in the rodent parasite Plasmodium berghei, showing that they play similar roles and supporting the usefulness of malaria mouse models.Mariana De NizAnn-Katrin UllrichArlett HeiberAlexandra Blancke SoaresChristian PickRuth LyckDerya KellerGesine KaiserMonica PradoSven FlemmingHernando del PortilloChris J. JanseVolker HeusslerTobias SpielmannNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Mariana De Niz
Ann-Katrin Ullrich
Arlett Heiber
Alexandra Blancke Soares
Christian Pick
Ruth Lyck
Derya Keller
Gesine Kaiser
Monica Prado
Sven Flemming
Hernando del Portillo
Chris J. Janse
Volker Heussler
Tobias Spielmann
The machinery underlying malaria parasite virulence is conserved between rodent and human malaria parasites
description Proteins SBP1 and MAHRP1 of the human malaria parasite are required for sequestration of infected red blood cells in major organs. Here, De Niz et al. identify homologous proteins in the rodent parasite Plasmodium berghei, showing that they play similar roles and supporting the usefulness of malaria mouse models.
format article
author Mariana De Niz
Ann-Katrin Ullrich
Arlett Heiber
Alexandra Blancke Soares
Christian Pick
Ruth Lyck
Derya Keller
Gesine Kaiser
Monica Prado
Sven Flemming
Hernando del Portillo
Chris J. Janse
Volker Heussler
Tobias Spielmann
author_facet Mariana De Niz
Ann-Katrin Ullrich
Arlett Heiber
Alexandra Blancke Soares
Christian Pick
Ruth Lyck
Derya Keller
Gesine Kaiser
Monica Prado
Sven Flemming
Hernando del Portillo
Chris J. Janse
Volker Heussler
Tobias Spielmann
author_sort Mariana De Niz
title The machinery underlying malaria parasite virulence is conserved between rodent and human malaria parasites
title_short The machinery underlying malaria parasite virulence is conserved between rodent and human malaria parasites
title_full The machinery underlying malaria parasite virulence is conserved between rodent and human malaria parasites
title_fullStr The machinery underlying malaria parasite virulence is conserved between rodent and human malaria parasites
title_full_unstemmed The machinery underlying malaria parasite virulence is conserved between rodent and human malaria parasites
title_sort machinery underlying malaria parasite virulence is conserved between rodent and human malaria parasites
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/ce5dde75c34e4b5ebcf04a7b660268c8
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