Stability and folding pathways of tetra-nucleosome from six-dimensional free energy surface
The three-dimensional organization of chromatin plays critical roles in regulating genome function. Here the authors apply a near atomistic model to study the structure and dynamics of the chromatin folding unit - the tetra-nucleosome - to provide insight into how chromatin folds.
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Nature Portfolio
2021
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oai:doaj.org-article:ce70e2bc0c774c9db71e82b9808904b72021-12-02T12:11:11ZStability and folding pathways of tetra-nucleosome from six-dimensional free energy surface10.1038/s41467-021-21377-z2041-1723https://doaj.org/article/ce70e2bc0c774c9db71e82b9808904b72021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21377-zhttps://doaj.org/toc/2041-1723The three-dimensional organization of chromatin plays critical roles in regulating genome function. Here the authors apply a near atomistic model to study the structure and dynamics of the chromatin folding unit - the tetra-nucleosome - to provide insight into how chromatin folds.Xinqiang DingXingcheng LinBin ZhangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021) |
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Science Q Xinqiang Ding Xingcheng Lin Bin Zhang Stability and folding pathways of tetra-nucleosome from six-dimensional free energy surface |
description |
The three-dimensional organization of chromatin plays critical roles in regulating genome function. Here the authors apply a near atomistic model to study the structure and dynamics of the chromatin folding unit - the tetra-nucleosome - to provide insight into how chromatin folds. |
format |
article |
author |
Xinqiang Ding Xingcheng Lin Bin Zhang |
author_facet |
Xinqiang Ding Xingcheng Lin Bin Zhang |
author_sort |
Xinqiang Ding |
title |
Stability and folding pathways of tetra-nucleosome from six-dimensional free energy surface |
title_short |
Stability and folding pathways of tetra-nucleosome from six-dimensional free energy surface |
title_full |
Stability and folding pathways of tetra-nucleosome from six-dimensional free energy surface |
title_fullStr |
Stability and folding pathways of tetra-nucleosome from six-dimensional free energy surface |
title_full_unstemmed |
Stability and folding pathways of tetra-nucleosome from six-dimensional free energy surface |
title_sort |
stability and folding pathways of tetra-nucleosome from six-dimensional free energy surface |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/ce70e2bc0c774c9db71e82b9808904b7 |
work_keys_str_mv |
AT xinqiangding stabilityandfoldingpathwaysoftetranucleosomefromsixdimensionalfreeenergysurface AT xingchenglin stabilityandfoldingpathwaysoftetranucleosomefromsixdimensionalfreeenergysurface AT binzhang stabilityandfoldingpathwaysoftetranucleosomefromsixdimensionalfreeenergysurface |
_version_ |
1718394658454765568 |