Tradict enables accurate prediction of eukaryotic transcriptional states from 100 marker genes
Global patterns of gene transcription can be represented with reduced dimensionality. Here, the authors devise a method called Tradict that learns and uses 100 marker genes to predict transcriptome-wide pathway expression levels and patterns that reflect cell activity and state.
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Nature Portfolio
2017
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oai:doaj.org-article:ce737e4cc0ea42049b5f81c9b37826b72021-12-02T17:06:25ZTradict enables accurate prediction of eukaryotic transcriptional states from 100 marker genes10.1038/ncomms153092041-1723https://doaj.org/article/ce737e4cc0ea42049b5f81c9b37826b72017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15309https://doaj.org/toc/2041-1723Global patterns of gene transcription can be represented with reduced dimensionality. Here, the authors devise a method called Tradict that learns and uses 100 marker genes to predict transcriptome-wide pathway expression levels and patterns that reflect cell activity and state.Surojit BiswasKonstantin KernerPaulo José Pereira Lima TeixeiraJeffery L. DanglVladimir JojicPhilip A. WiggeNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Surojit Biswas Konstantin Kerner Paulo José Pereira Lima Teixeira Jeffery L. Dangl Vladimir Jojic Philip A. Wigge Tradict enables accurate prediction of eukaryotic transcriptional states from 100 marker genes |
| description |
Global patterns of gene transcription can be represented with reduced dimensionality. Here, the authors devise a method called Tradict that learns and uses 100 marker genes to predict transcriptome-wide pathway expression levels and patterns that reflect cell activity and state. |
| format |
article |
| author |
Surojit Biswas Konstantin Kerner Paulo José Pereira Lima Teixeira Jeffery L. Dangl Vladimir Jojic Philip A. Wigge |
| author_facet |
Surojit Biswas Konstantin Kerner Paulo José Pereira Lima Teixeira Jeffery L. Dangl Vladimir Jojic Philip A. Wigge |
| author_sort |
Surojit Biswas |
| title |
Tradict enables accurate prediction of eukaryotic transcriptional states from 100 marker genes |
| title_short |
Tradict enables accurate prediction of eukaryotic transcriptional states from 100 marker genes |
| title_full |
Tradict enables accurate prediction of eukaryotic transcriptional states from 100 marker genes |
| title_fullStr |
Tradict enables accurate prediction of eukaryotic transcriptional states from 100 marker genes |
| title_full_unstemmed |
Tradict enables accurate prediction of eukaryotic transcriptional states from 100 marker genes |
| title_sort |
tradict enables accurate prediction of eukaryotic transcriptional states from 100 marker genes |
| publisher |
Nature Portfolio |
| publishDate |
2017 |
| url |
https://doaj.org/article/ce737e4cc0ea42049b5f81c9b37826b7 |
| work_keys_str_mv |
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| _version_ |
1718381640032452608 |