Homocysteine Impairs Endothelial Cell Barrier Function and Angiogenic Potential via the Progranulin/EphA2 Pathway
Hyperhomocysteinemia is a well-recognized independent risk factor for cardiovascular disease. To date, the mechanism of pathological plasma homocysteine (Hcy) level elevation remains to be elucidated. We aimed to investigate the levels of progranulin (PGRN), Eph-receptor tyrosine kinase-type A2 (Eph...
Saved in:
Main Authors: | Dan Tian, Qing Qin, Mingfei Li, Xiaoyu Li, Qing Xu, Qianzhou Lv |
---|---|
Format: | article |
Language: | EN |
Published: |
Frontiers Media S.A.
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/ce74aec2fdb74bf69011df5ed52fe1ab |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
EphA2 Expression in Bone Sarcomas: Bioinformatic Analyses and Preclinical Characterization in Patient-Derived Models of Osteosarcoma, Ewing’s Sarcoma and Chondrosarcoma
by: Giorgia Giordano, et al.
Published: (2021) -
Anti-EphA10 antibody-conjugated pH-sensitive liposomes for specific intracellular delivery of siRNA
by: Zang X, et al.
Published: (2016) -
Codelivery of doxorubicin and JIP1 siRNA with novel EphA2-targeted PEGylated cationic nanoliposomes to overcome osteosarcoma multidrug resistance
by: Haghiralsadat F, et al.
Published: (2018) -
Eph-ephrin Signaling Affects Eye Lens Fiber Cell Intracellular Voltage and Membrane Conductance
by: Catherine Cheng, et al.
Published: (2021) -
Interplay of Eph-Ephrin Signalling and Cadherin Function in Cell Segregation and Boundary Formation
by: David G. Wilkinson
Published: (2021)