The Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon
NCOMMS-19-38235B Dorsal-ventral patterning of the mammalian telencephalon is fundamental to the formation of distinct functional regions. Here, the authors find that PcG proteins suppress BMP and Wnt signaling in a region-specific manner, allowing for proper Shh expression and development of the ven...
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Nature Portfolio
2020
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oai:doaj.org-article:ce804acfbc32428c8f42eaeed912e0a02021-12-02T14:42:47ZThe Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon10.1038/s41467-020-19556-52041-1723https://doaj.org/article/ce804acfbc32428c8f42eaeed912e0a02020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19556-5https://doaj.org/toc/2041-1723NCOMMS-19-38235B Dorsal-ventral patterning of the mammalian telencephalon is fundamental to the formation of distinct functional regions. Here, the authors find that PcG proteins suppress BMP and Wnt signaling in a region-specific manner, allowing for proper Shh expression and development of the ventral telencephalon.Hikaru EtoYusuke KishiNayuta Yakushiji-KaminatsuiHiroki SugishitaShun UtsunomiyaHaruhiko KosekiYukiko GotohNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020) |
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Science Q Hikaru Eto Yusuke Kishi Nayuta Yakushiji-Kaminatsui Hiroki Sugishita Shun Utsunomiya Haruhiko Koseki Yukiko Gotoh The Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon |
description |
NCOMMS-19-38235B Dorsal-ventral patterning of the mammalian telencephalon is fundamental to the formation of distinct functional regions. Here, the authors find that PcG proteins suppress BMP and Wnt signaling in a region-specific manner, allowing for proper Shh expression and development of the ventral telencephalon. |
format |
article |
author |
Hikaru Eto Yusuke Kishi Nayuta Yakushiji-Kaminatsui Hiroki Sugishita Shun Utsunomiya Haruhiko Koseki Yukiko Gotoh |
author_facet |
Hikaru Eto Yusuke Kishi Nayuta Yakushiji-Kaminatsui Hiroki Sugishita Shun Utsunomiya Haruhiko Koseki Yukiko Gotoh |
author_sort |
Hikaru Eto |
title |
The Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon |
title_short |
The Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon |
title_full |
The Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon |
title_fullStr |
The Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon |
title_full_unstemmed |
The Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon |
title_sort |
polycomb group protein ring1 regulates dorsoventral patterning of the mouse telencephalon |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/ce804acfbc32428c8f42eaeed912e0a0 |
work_keys_str_mv |
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