The Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon

NCOMMS-19-38235B Dorsal-ventral patterning of the mammalian telencephalon is fundamental to the formation of distinct functional regions. Here, the authors find that PcG proteins suppress BMP and Wnt signaling in a region-specific manner, allowing for proper Shh expression and development of the ven...

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Autores principales: Hikaru Eto, Yusuke Kishi, Nayuta Yakushiji-Kaminatsui, Hiroki Sugishita, Shun Utsunomiya, Haruhiko Koseki, Yukiko Gotoh
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/ce804acfbc32428c8f42eaeed912e0a0
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spelling oai:doaj.org-article:ce804acfbc32428c8f42eaeed912e0a02021-12-02T14:42:47ZThe Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon10.1038/s41467-020-19556-52041-1723https://doaj.org/article/ce804acfbc32428c8f42eaeed912e0a02020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19556-5https://doaj.org/toc/2041-1723NCOMMS-19-38235B Dorsal-ventral patterning of the mammalian telencephalon is fundamental to the formation of distinct functional regions. Here, the authors find that PcG proteins suppress BMP and Wnt signaling in a region-specific manner, allowing for proper Shh expression and development of the ventral telencephalon.Hikaru EtoYusuke KishiNayuta Yakushiji-KaminatsuiHiroki SugishitaShun UtsunomiyaHaruhiko KosekiYukiko GotohNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Hikaru Eto
Yusuke Kishi
Nayuta Yakushiji-Kaminatsui
Hiroki Sugishita
Shun Utsunomiya
Haruhiko Koseki
Yukiko Gotoh
The Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon
description NCOMMS-19-38235B Dorsal-ventral patterning of the mammalian telencephalon is fundamental to the formation of distinct functional regions. Here, the authors find that PcG proteins suppress BMP and Wnt signaling in a region-specific manner, allowing for proper Shh expression and development of the ventral telencephalon.
format article
author Hikaru Eto
Yusuke Kishi
Nayuta Yakushiji-Kaminatsui
Hiroki Sugishita
Shun Utsunomiya
Haruhiko Koseki
Yukiko Gotoh
author_facet Hikaru Eto
Yusuke Kishi
Nayuta Yakushiji-Kaminatsui
Hiroki Sugishita
Shun Utsunomiya
Haruhiko Koseki
Yukiko Gotoh
author_sort Hikaru Eto
title The Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon
title_short The Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon
title_full The Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon
title_fullStr The Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon
title_full_unstemmed The Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon
title_sort polycomb group protein ring1 regulates dorsoventral patterning of the mouse telencephalon
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/ce804acfbc32428c8f42eaeed912e0a0
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