Importance of human leukocyte antigen (HLA) class I and II alleles on the risk of multiple sclerosis.

Importance of human leukocyte antigen (HLA) class I and II alleles on the risk of multiple sclerosis.

Multiple sclerosis (MS) is a complex disease of the central nervous system of unknown etiology. The human leukocyte antigen (HLA) locus on chromosome 6 confers a considerable part of the susceptibility to MS, and the most important factor is the class II allele HLA-DRB1*15:01. In addition, we and ot...

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Autores principales: Jenny Link, Ingrid Kockum, Aslaug R Lorentzen, Benedicte A Lie, Elisabeth G Celius, Helga Westerlind, Marie Schaffer, Lars Alfredsson, Tomas Olsson, Boel Brynedal, Hanne F Harbo, Jan Hillert
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/ce8709991332409eae1ce68f6558e569
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