An Exceptional Etiology of a Rare Disease: Pneumatosis Intestinalis in the Intensive Care Unit due to Chronic Graft-Versus-Host Disease

Pneumatosis intestinalis (PI) is a rare disease, which presents a wide range of severity. Numerous etiologies, including trauma, inflammation, infections, autoimmunity, drugs, and mechanical procedures, gave rise to this complication. Abdominal computerized tomography is the preferred diagnostic too...

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Autores principales:	Taner Çalışkan, Hüseyin Özkök, Murat Küçük, Beril Turan Erdoğan, Vedat Uygun, Yusuf Savran, Bilgin Cömert
Formato:	article
Lenguaje:	EN TR
Publicado:	Galenos Yayinevi 2021
Materias:	chronic graft versus host disease pneumatosis intestinalis intensive care Medicine R Internal medicine RC31-1245 Medical emergencies. Critical care. Intensive care. First aid RC86-88.9
Acceso en línea:	https://doaj.org/article/ce8742c3bd0d4ec3bd45d2e214c895a0
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spelling	oai:doaj.org-article:ce8742c3bd0d4ec3bd45d2e214c895a02021-11-23T10:33:41ZAn Exceptional Etiology of a Rare Disease: Pneumatosis Intestinalis in the Intensive Care Unit due to Chronic Graft-Versus-Host Disease2146-64162147-267X10.4274/tybd.galenos.2021.55265https://doaj.org/article/ce8742c3bd0d4ec3bd45d2e214c895a02021-12-01T00:00:00Z http://www.turkishjic.org/archives/archive-detail/article-preview/an-exceptional-etiology-of-a-rare-disease-pneumato/49036 https://doaj.org/toc/2146-6416https://doaj.org/toc/2147-267XPneumatosis intestinalis (PI) is a rare disease, which presents a wide range of severity. Numerous etiologies, including trauma, inflammation, infections, autoimmunity, drugs, and mechanical procedures, gave rise to this complication. Abdominal computerized tomography is the preferred diagnostic tool with high sensitivity. The diagnosis depends on free air detection in the intramural portion of the gastrointestinal system and main and intrahepatic branches of the portal venous structures. However, the exact mechanism is unknown. The clinical scenario may vary from benign to life-threatening. One of the etiological factors that cause PI is the chronic graft-versus-host disease (cGVHD), which must be considered in patients with solid organ or hematological malignancies. Especially, patients who received long-term immunosuppressive therapies and were diagnosed with cGVHD are prone to developing a PI. Many patients experience unnecessary operational risks if underdiagnosed. A multidisciplinary approach by the primary physician, general surgeon, and radiology specialist is necessary for the proper treatment of these patients. This case report aimed to discuss the clinical presentation of PI in the course of cGVHD in the intensive care unit.Taner ÇalışkanHüseyin ÖzkökMurat KüçükBeril Turan ErdoğanVedat UygunYusuf SavranBilgin CömertGalenos Yayineviarticlechronic graft versus host diseasepneumatosis intestinalisintensive careMedicineRInternal medicineRC31-1245Medical emergencies. Critical care. Intensive care. First aidRC86-88.9ENTRTürk Yoğun Bakim Derneği Dergisi, Vol 19, Iss 4, Pp 200-204 (2021)
institution	DOAJ
collection	DOAJ
language	EN TR
topic	chronic graft versus host disease pneumatosis intestinalis intensive care Medicine R Internal medicine RC31-1245 Medical emergencies. Critical care. Intensive care. First aid RC86-88.9
spellingShingle	chronic graft versus host disease pneumatosis intestinalis intensive care Medicine R Internal medicine RC31-1245 Medical emergencies. Critical care. Intensive care. First aid RC86-88.9 Taner Çalışkan Hüseyin Özkök Murat Küçük Beril Turan Erdoğan Vedat Uygun Yusuf Savran Bilgin Cömert An Exceptional Etiology of a Rare Disease: Pneumatosis Intestinalis in the Intensive Care Unit due to Chronic Graft-Versus-Host Disease
description	Pneumatosis intestinalis (PI) is a rare disease, which presents a wide range of severity. Numerous etiologies, including trauma, inflammation, infections, autoimmunity, drugs, and mechanical procedures, gave rise to this complication. Abdominal computerized tomography is the preferred diagnostic tool with high sensitivity. The diagnosis depends on free air detection in the intramural portion of the gastrointestinal system and main and intrahepatic branches of the portal venous structures. However, the exact mechanism is unknown. The clinical scenario may vary from benign to life-threatening. One of the etiological factors that cause PI is the chronic graft-versus-host disease (cGVHD), which must be considered in patients with solid organ or hematological malignancies. Especially, patients who received long-term immunosuppressive therapies and were diagnosed with cGVHD are prone to developing a PI. Many patients experience unnecessary operational risks if underdiagnosed. A multidisciplinary approach by the primary physician, general surgeon, and radiology specialist is necessary for the proper treatment of these patients. This case report aimed to discuss the clinical presentation of PI in the course of cGVHD in the intensive care unit.
format	article
author	Taner Çalışkan Hüseyin Özkök Murat Küçük Beril Turan Erdoğan Vedat Uygun Yusuf Savran Bilgin Cömert
author_facet	Taner Çalışkan Hüseyin Özkök Murat Küçük Beril Turan Erdoğan Vedat Uygun Yusuf Savran Bilgin Cömert
author_sort	Taner Çalışkan
title	An Exceptional Etiology of a Rare Disease: Pneumatosis Intestinalis in the Intensive Care Unit due to Chronic Graft-Versus-Host Disease
title_short	An Exceptional Etiology of a Rare Disease: Pneumatosis Intestinalis in the Intensive Care Unit due to Chronic Graft-Versus-Host Disease
title_full	An Exceptional Etiology of a Rare Disease: Pneumatosis Intestinalis in the Intensive Care Unit due to Chronic Graft-Versus-Host Disease
title_fullStr	An Exceptional Etiology of a Rare Disease: Pneumatosis Intestinalis in the Intensive Care Unit due to Chronic Graft-Versus-Host Disease
title_full_unstemmed	An Exceptional Etiology of a Rare Disease: Pneumatosis Intestinalis in the Intensive Care Unit due to Chronic Graft-Versus-Host Disease
title_sort	exceptional etiology of a rare disease: pneumatosis intestinalis in the intensive care unit due to chronic graft-versus-host disease
publisher	Galenos Yayinevi
publishDate	2021
url	https://doaj.org/article/ce8742c3bd0d4ec3bd45d2e214c895a0
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An Exceptional Etiology of a Rare Disease: Pneumatosis Intestinalis in the Intensive Care Unit due to Chronic Graft-Versus-Host Disease

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