Optimization of Hydroxy Propyl Methyl Cellulose and Carbomer In Diltiazem Hydrochloride Mucoadhesive Buccal Film
Diltiazem hydrochloride (HCl) is a category of calcium channel blocker used as an antihypertensive agent. Diltiazem HCl is a low bioavailable drug due to high first-pass metabolism and a short half-life (3-5 hours); hence mucoadhesive buccal film was made to overcome this weakness. Bioavailability o...
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Autores principales: | Lina Winarti, Bagus Tri Laksono, Lusia Oktora Ruma Kumala Sari |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Universitas Gadjah Mada
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/ce890bae53764b069f052f2b421507c4 |
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