Optimization of Hydroxy Propyl Methyl Cellulose and Carbomer In Diltiazem Hydrochloride Mucoadhesive Buccal Film
Diltiazem hydrochloride (HCl) is a category of calcium channel blocker used as an antihypertensive agent. Diltiazem HCl is a low bioavailable drug due to high first-pass metabolism and a short half-life (3-5 hours); hence mucoadhesive buccal film was made to overcome this weakness. Bioavailability o...
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| Main Authors: | , , |
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| Format: | article |
| Language: | EN |
| Published: |
Universitas Gadjah Mada
2021
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| Subjects: | |
| Online Access: | https://doaj.org/article/ce890bae53764b069f052f2b421507c4 |
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