Global genetic differentiation of complex traits shaped by natural selection in humans
Human complex traits and disorders often show differentiation among populations. Here, the authors analyze SNPs associated with 10 complex traits using data of large sample size from African, East Asian and European populations, and find significant genetic differentiation among global populations s...
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Nature Portfolio
2018
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oai:doaj.org-article:ce8f0f0642324bfbada7286562402d0f2021-12-02T14:39:25ZGlobal genetic differentiation of complex traits shaped by natural selection in humans10.1038/s41467-018-04191-y2041-1723https://doaj.org/article/ce8f0f0642324bfbada7286562402d0f2018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04191-yhttps://doaj.org/toc/2041-1723Human complex traits and disorders often show differentiation among populations. Here, the authors analyze SNPs associated with 10 complex traits using data of large sample size from African, East Asian and European populations, and find significant genetic differentiation among global populations shaped by natural selection.Jing GuoYang WuZhihong ZhuZhili ZhengMaciej TrzaskowskiJian ZengMatthew R. RobinsonPeter M. VisscherJian YangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018) |
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Science Q Jing Guo Yang Wu Zhihong Zhu Zhili Zheng Maciej Trzaskowski Jian Zeng Matthew R. Robinson Peter M. Visscher Jian Yang Global genetic differentiation of complex traits shaped by natural selection in humans |
description |
Human complex traits and disorders often show differentiation among populations. Here, the authors analyze SNPs associated with 10 complex traits using data of large sample size from African, East Asian and European populations, and find significant genetic differentiation among global populations shaped by natural selection. |
format |
article |
author |
Jing Guo Yang Wu Zhihong Zhu Zhili Zheng Maciej Trzaskowski Jian Zeng Matthew R. Robinson Peter M. Visscher Jian Yang |
author_facet |
Jing Guo Yang Wu Zhihong Zhu Zhili Zheng Maciej Trzaskowski Jian Zeng Matthew R. Robinson Peter M. Visscher Jian Yang |
author_sort |
Jing Guo |
title |
Global genetic differentiation of complex traits shaped by natural selection in humans |
title_short |
Global genetic differentiation of complex traits shaped by natural selection in humans |
title_full |
Global genetic differentiation of complex traits shaped by natural selection in humans |
title_fullStr |
Global genetic differentiation of complex traits shaped by natural selection in humans |
title_full_unstemmed |
Global genetic differentiation of complex traits shaped by natural selection in humans |
title_sort |
global genetic differentiation of complex traits shaped by natural selection in humans |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/ce8f0f0642324bfbada7286562402d0f |
work_keys_str_mv |
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_version_ |
1718390619276050432 |