Global genetic differentiation of complex traits shaped by natural selection in humans

Human complex traits and disorders often show differentiation among populations. Here, the authors analyze SNPs associated with 10 complex traits using data of large sample size from African, East Asian and European populations, and find significant genetic differentiation among global populations s...

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Main Authors:	Jing Guo, Yang Wu, Zhihong Zhu, Zhili Zheng, Maciej Trzaskowski, Jian Zeng, Matthew R. Robinson, Peter M. Visscher, Jian Yang
Format:	article
Language:	EN
Published:	Nature Portfolio 2018
Subjects:	Science Q
Online Access:	https://doaj.org/article/ce8f0f0642324bfbada7286562402d0f
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spelling	oai:doaj.org-article:ce8f0f0642324bfbada7286562402d0f2021-12-02T14:39:25ZGlobal genetic differentiation of complex traits shaped by natural selection in humans10.1038/s41467-018-04191-y2041-1723https://doaj.org/article/ce8f0f0642324bfbada7286562402d0f2018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04191-yhttps://doaj.org/toc/2041-1723Human complex traits and disorders often show differentiation among populations. Here, the authors analyze SNPs associated with 10 complex traits using data of large sample size from African, East Asian and European populations, and find significant genetic differentiation among global populations shaped by natural selection.Jing GuoYang WuZhihong ZhuZhili ZhengMaciej TrzaskowskiJian ZengMatthew R. RobinsonPeter M. VisscherJian YangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jing Guo Yang Wu Zhihong Zhu Zhili Zheng Maciej Trzaskowski Jian Zeng Matthew R. Robinson Peter M. Visscher Jian Yang Global genetic differentiation of complex traits shaped by natural selection in humans
description	Human complex traits and disorders often show differentiation among populations. Here, the authors analyze SNPs associated with 10 complex traits using data of large sample size from African, East Asian and European populations, and find significant genetic differentiation among global populations shaped by natural selection.
format	article
author	Jing Guo Yang Wu Zhihong Zhu Zhili Zheng Maciej Trzaskowski Jian Zeng Matthew R. Robinson Peter M. Visscher Jian Yang
author_facet	Jing Guo Yang Wu Zhihong Zhu Zhili Zheng Maciej Trzaskowski Jian Zeng Matthew R. Robinson Peter M. Visscher Jian Yang
author_sort	Jing Guo
title	Global genetic differentiation of complex traits shaped by natural selection in humans
title_short	Global genetic differentiation of complex traits shaped by natural selection in humans
title_full	Global genetic differentiation of complex traits shaped by natural selection in humans
title_fullStr	Global genetic differentiation of complex traits shaped by natural selection in humans
title_full_unstemmed	Global genetic differentiation of complex traits shaped by natural selection in humans
title_sort	global genetic differentiation of complex traits shaped by natural selection in humans
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/ce8f0f0642324bfbada7286562402d0f
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Global genetic differentiation of complex traits shaped by natural selection in humans

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