Microtubule end conversion mediated by motors and diffusing proteins with no intrinsic microtubule end-binding activity

During cell division, it is currently unclear how kinetochores transit from lateral microtubule attachment to durable association to dynamic microtubule plus ends. Here, using in vitro reconstitution and computer modeling, the authors provide biophysical mechanism for microtubule end-conversion driv...

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Autores principales:	Manas Chakraborty, Ekaterina V. Tarasovetc, Anatoly V. Zaytsev, Maxim Godzi, Ana C. Figueiredo, Fazly I. Ataullakhanov, Ekaterina L. Grishchuk
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ce917114ab1d4d2a9499e8a6eb19865d
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spelling	oai:doaj.org-article:ce917114ab1d4d2a9499e8a6eb19865d2021-12-02T14:35:56ZMicrotubule end conversion mediated by motors and diffusing proteins with no intrinsic microtubule end-binding activity10.1038/s41467-019-09411-72041-1723https://doaj.org/article/ce917114ab1d4d2a9499e8a6eb19865d2019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09411-7https://doaj.org/toc/2041-1723During cell division, it is currently unclear how kinetochores transit from lateral microtubule attachment to durable association to dynamic microtubule plus ends. Here, using in vitro reconstitution and computer modeling, the authors provide biophysical mechanism for microtubule end-conversion driven by two kinetochore components, CENP-E and Ndc80 complexManas ChakrabortyEkaterina V. TarasovetcAnatoly V. ZaytsevMaxim GodziAna C. FigueiredoFazly I. AtaullakhanovEkaterina L. GrishchukNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Manas Chakraborty Ekaterina V. Tarasovetc Anatoly V. Zaytsev Maxim Godzi Ana C. Figueiredo Fazly I. Ataullakhanov Ekaterina L. Grishchuk Microtubule end conversion mediated by motors and diffusing proteins with no intrinsic microtubule end-binding activity
description	During cell division, it is currently unclear how kinetochores transit from lateral microtubule attachment to durable association to dynamic microtubule plus ends. Here, using in vitro reconstitution and computer modeling, the authors provide biophysical mechanism for microtubule end-conversion driven by two kinetochore components, CENP-E and Ndc80 complex
format	article
author	Manas Chakraborty Ekaterina V. Tarasovetc Anatoly V. Zaytsev Maxim Godzi Ana C. Figueiredo Fazly I. Ataullakhanov Ekaterina L. Grishchuk
author_facet	Manas Chakraborty Ekaterina V. Tarasovetc Anatoly V. Zaytsev Maxim Godzi Ana C. Figueiredo Fazly I. Ataullakhanov Ekaterina L. Grishchuk
author_sort	Manas Chakraborty
title	Microtubule end conversion mediated by motors and diffusing proteins with no intrinsic microtubule end-binding activity
title_short	Microtubule end conversion mediated by motors and diffusing proteins with no intrinsic microtubule end-binding activity
title_full	Microtubule end conversion mediated by motors and diffusing proteins with no intrinsic microtubule end-binding activity
title_fullStr	Microtubule end conversion mediated by motors and diffusing proteins with no intrinsic microtubule end-binding activity
title_full_unstemmed	Microtubule end conversion mediated by motors and diffusing proteins with no intrinsic microtubule end-binding activity
title_sort	microtubule end conversion mediated by motors and diffusing proteins with no intrinsic microtubule end-binding activity
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/ce917114ab1d4d2a9499e8a6eb19865d
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Microtubule end conversion mediated by motors and diffusing proteins with no intrinsic microtubule end-binding activity

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