Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7
Skeletal muscle stem cells express the transcription factor Pax7. Here, the authors isolate, from human muscle, cells that are positive for the endothelial marker CLEC14A and show that despite not expressing pax7, these cells regenerate muscle and contribute to the muscle stem cell niche when transp...
Enregistré dans:
Auteurs principaux: | Andreas Marg, Helena Escobar, Nikos Karaiskos, Stefanie A. Grunwald, Eric Metzler, Janine Kieshauer, Sascha Sauer, Diana Pasemann, Edoardo Malfatti, Dominique Mompoint, Susanna Quijano-Roy, Anastasiya Boltengagen, Joanna Schneider, Markus Schülke, Séverine Kunz, Robert Carlier, Carmen Birchmeier, Helge Amthor, Andreas Spuler, Christine Kocks, Nikolaus Rajewsky, Simone Spuler |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2019
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/ce96cb57dae14384b0b97d2a3e6fda84 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Altered expression of cyclin A 1 in muscle of patients with facioscapulohumeral muscle dystrophy (FSHD-1).
par: Anna Pakula, et autres
Publié: (2013) -
Single-nucleus transcriptomics reveals functional compartmentalization in syncytial skeletal muscle cells
par: Minchul Kim, et autres
Publié: (2020) -
Dysferlin-peptides reallocate mutated dysferlin thereby restoring function.
par: Verena Schoewel, et autres
Publié: (2012) -
PAX7 target genes are globally repressed in facioscapulohumeral muscular dystrophy skeletal muscle
par: Christopher R. S. Banerji, et autres
Publié: (2017) -
Acetylation of PAX7 controls muscle stem cell self-renewal and differentiation potential in mice
par: Marie-Claude Sincennes, et autres
Publié: (2021)