Pan-cancer analysis of transcriptional metabolic dysregulation using The Cancer Genome Atlas
Metabolism is frequently dysregulated in cancer. Here, the authors conduct a pan-cancer analysis of The Cancer Genome Atlas to determine significant metabolic pathway alterations, highlight master metabolic transcriptional regulators, and predict patient response to metabolism targeted-therapeutics
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Autores principales: | , , , , , |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/ce96fd232aac40bf8ffdc092b138dab3 |
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Sumario: | Metabolism is frequently dysregulated in cancer. Here, the authors conduct a pan-cancer analysis of The Cancer Genome Atlas to determine significant metabolic pathway alterations, highlight master metabolic transcriptional regulators, and predict patient response to metabolism targeted-therapeutics |
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