Pan-cancer analysis of transcriptional metabolic dysregulation using The Cancer Genome Atlas

Metabolism is frequently dysregulated in cancer. Here, the authors conduct a pan-cancer analysis of The Cancer Genome Atlas to determine significant metabolic pathway alterations, highlight master metabolic transcriptional regulators, and predict patient response to metabolism targeted-therapeutics

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Detalles Bibliográficos
Autores principales:	S. R. Rosario, M. D. Long, H. C. Affronti, A. M. Rowsam, K. H. Eng, D. J. Smiraglia
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ce96fd232aac40bf8ffdc092b138dab3
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spelling	oai:doaj.org-article:ce96fd232aac40bf8ffdc092b138dab32021-12-02T16:50:09ZPan-cancer analysis of transcriptional metabolic dysregulation using The Cancer Genome Atlas10.1038/s41467-018-07232-82041-1723https://doaj.org/article/ce96fd232aac40bf8ffdc092b138dab32018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07232-8https://doaj.org/toc/2041-1723Metabolism is frequently dysregulated in cancer. Here, the authors conduct a pan-cancer analysis of The Cancer Genome Atlas to determine significant metabolic pathway alterations, highlight master metabolic transcriptional regulators, and predict patient response to metabolism targeted-therapeuticsS. R. RosarioM. D. LongH. C. AffrontiA. M. RowsamK. H. EngD. J. SmiragliaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q S. R. Rosario M. D. Long H. C. Affronti A. M. Rowsam K. H. Eng D. J. Smiraglia Pan-cancer analysis of transcriptional metabolic dysregulation using The Cancer Genome Atlas
description	Metabolism is frequently dysregulated in cancer. Here, the authors conduct a pan-cancer analysis of The Cancer Genome Atlas to determine significant metabolic pathway alterations, highlight master metabolic transcriptional regulators, and predict patient response to metabolism targeted-therapeutics
format	article
author	S. R. Rosario M. D. Long H. C. Affronti A. M. Rowsam K. H. Eng D. J. Smiraglia
author_facet	S. R. Rosario M. D. Long H. C. Affronti A. M. Rowsam K. H. Eng D. J. Smiraglia
author_sort	S. R. Rosario
title	Pan-cancer analysis of transcriptional metabolic dysregulation using The Cancer Genome Atlas
title_short	Pan-cancer analysis of transcriptional metabolic dysregulation using The Cancer Genome Atlas
title_full	Pan-cancer analysis of transcriptional metabolic dysregulation using The Cancer Genome Atlas
title_fullStr	Pan-cancer analysis of transcriptional metabolic dysregulation using The Cancer Genome Atlas
title_full_unstemmed	Pan-cancer analysis of transcriptional metabolic dysregulation using The Cancer Genome Atlas
title_sort	pan-cancer analysis of transcriptional metabolic dysregulation using the cancer genome atlas
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/ce96fd232aac40bf8ffdc092b138dab3
work_keys_str_mv	AT srrosario pancanceranalysisoftranscriptionalmetabolicdysregulationusingthecancergenomeatlas AT mdlong pancanceranalysisoftranscriptionalmetabolicdysregulationusingthecancergenomeatlas AT hcaffronti pancanceranalysisoftranscriptionalmetabolicdysregulationusingthecancergenomeatlas AT amrowsam pancanceranalysisoftranscriptionalmetabolicdysregulationusingthecancergenomeatlas AT kheng pancanceranalysisoftranscriptionalmetabolicdysregulationusingthecancergenomeatlas AT djsmiraglia pancanceranalysisoftranscriptionalmetabolicdysregulationusingthecancergenomeatlas
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Pan-cancer analysis of transcriptional metabolic dysregulation using The Cancer Genome Atlas

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