Comparison of clinical severity and epidemiological spectrum between coronavirus disease 2019 and influenza in children

Abstract Data on the novel coronavirus disease 2019 (COVID-19) in children are limited, and studies from Europe are scarce. We analyzed the clinical severity and epidemiologic aspects of COVID-19 in consecutive children aged 0–18 years, referred with a suspicion of COVID-19 between February 1, and A...

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Autores principales:	Maria Pokorska-Śpiewak, Ewa Talarek, Jolanta Popielska, Karolina Nowicka, Agnieszka Ołdakowska, Konrad Zawadka, Barbara Kowalik-Mikołajewska, Anna Tomasik, Anna Dobrzeniecka, Marta Lipińska, Beata Krynicka-Czech, Urszula Coupland, Aleksandra Stańska-Perka, Małgorzata Ludek, Magdalena Marczyńska
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/ce9b6537cea841d482bd61cbe870b642
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spelling	oai:doaj.org-article:ce9b6537cea841d482bd61cbe870b6422021-12-02T13:33:51ZComparison of clinical severity and epidemiological spectrum between coronavirus disease 2019 and influenza in children10.1038/s41598-021-85340-02045-2322https://doaj.org/article/ce9b6537cea841d482bd61cbe870b6422021-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-85340-0https://doaj.org/toc/2045-2322Abstract Data on the novel coronavirus disease 2019 (COVID-19) in children are limited, and studies from Europe are scarce. We analyzed the clinical severity and epidemiologic aspects of COVID-19 in consecutive children aged 0–18 years, referred with a suspicion of COVID-19 between February 1, and April 15, 2020. RT-PCR on a nasopharyngeal swab was used to confirm COVID-19. 319 children met the criteria of a suspected case. COVID-19 was diagnosed in 15/319 (4.7%) patients (8 male; mean age 10.5 years). All of them had household contact with an infected relative. Five (33.3%) patients were asymptomatic. In 9/15 (60.0%) children, the course of the disease was mild, and in 1/15 (6.7%), it was moderate, with the following symptoms: fever (46.7%), cough (40%), diarrhea (20%), vomiting (13.3%), rhinitis (6.7%), and shortness of breath (6.7%). In the COVID-19-negative patients, other infections were confirmed, including influenza in 32/319 (10%). The clinical course of COVID-19 and influenza differed significantly based on the clinical presentation. In conclusion, the clinical course of COVID-19 in children is usually mild or asymptomatic. In children suspected of having COVID-19, other infections should not be overlooked. The main risk factor for COVID-19 in children is household contact with an infected relative.Maria Pokorska-ŚpiewakEwa TalarekJolanta PopielskaKarolina NowickaAgnieszka OłdakowskaKonrad ZawadkaBarbara Kowalik-MikołajewskaAnna TomasikAnna DobrzenieckaMarta LipińskaBeata Krynicka-CzechUrszula CouplandAleksandra Stańska-PerkaMałgorzata LudekMagdalena MarczyńskaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Maria Pokorska-Śpiewak Ewa Talarek Jolanta Popielska Karolina Nowicka Agnieszka Ołdakowska Konrad Zawadka Barbara Kowalik-Mikołajewska Anna Tomasik Anna Dobrzeniecka Marta Lipińska Beata Krynicka-Czech Urszula Coupland Aleksandra Stańska-Perka Małgorzata Ludek Magdalena Marczyńska Comparison of clinical severity and epidemiological spectrum between coronavirus disease 2019 and influenza in children
description	Abstract Data on the novel coronavirus disease 2019 (COVID-19) in children are limited, and studies from Europe are scarce. We analyzed the clinical severity and epidemiologic aspects of COVID-19 in consecutive children aged 0–18 years, referred with a suspicion of COVID-19 between February 1, and April 15, 2020. RT-PCR on a nasopharyngeal swab was used to confirm COVID-19. 319 children met the criteria of a suspected case. COVID-19 was diagnosed in 15/319 (4.7%) patients (8 male; mean age 10.5 years). All of them had household contact with an infected relative. Five (33.3%) patients were asymptomatic. In 9/15 (60.0%) children, the course of the disease was mild, and in 1/15 (6.7%), it was moderate, with the following symptoms: fever (46.7%), cough (40%), diarrhea (20%), vomiting (13.3%), rhinitis (6.7%), and shortness of breath (6.7%). In the COVID-19-negative patients, other infections were confirmed, including influenza in 32/319 (10%). The clinical course of COVID-19 and influenza differed significantly based on the clinical presentation. In conclusion, the clinical course of COVID-19 in children is usually mild or asymptomatic. In children suspected of having COVID-19, other infections should not be overlooked. The main risk factor for COVID-19 in children is household contact with an infected relative.
format	article
author	Maria Pokorska-Śpiewak Ewa Talarek Jolanta Popielska Karolina Nowicka Agnieszka Ołdakowska Konrad Zawadka Barbara Kowalik-Mikołajewska Anna Tomasik Anna Dobrzeniecka Marta Lipińska Beata Krynicka-Czech Urszula Coupland Aleksandra Stańska-Perka Małgorzata Ludek Magdalena Marczyńska
author_facet	Maria Pokorska-Śpiewak Ewa Talarek Jolanta Popielska Karolina Nowicka Agnieszka Ołdakowska Konrad Zawadka Barbara Kowalik-Mikołajewska Anna Tomasik Anna Dobrzeniecka Marta Lipińska Beata Krynicka-Czech Urszula Coupland Aleksandra Stańska-Perka Małgorzata Ludek Magdalena Marczyńska
author_sort	Maria Pokorska-Śpiewak
title	Comparison of clinical severity and epidemiological spectrum between coronavirus disease 2019 and influenza in children
title_short	Comparison of clinical severity and epidemiological spectrum between coronavirus disease 2019 and influenza in children
title_full	Comparison of clinical severity and epidemiological spectrum between coronavirus disease 2019 and influenza in children
title_fullStr	Comparison of clinical severity and epidemiological spectrum between coronavirus disease 2019 and influenza in children
title_full_unstemmed	Comparison of clinical severity and epidemiological spectrum between coronavirus disease 2019 and influenza in children
title_sort	comparison of clinical severity and epidemiological spectrum between coronavirus disease 2019 and influenza in children
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/ce9b6537cea841d482bd61cbe870b642
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Comparison of clinical severity and epidemiological spectrum between coronavirus disease 2019 and influenza in children

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