USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components

The ubiquitin-proteasome system regulates cellular reprogramming by degradation of key pluripotency factors. Here the authors report that the post-translational regulation of PRC1 components CBX4 and CBX6 by ubiquitination influences reprogramming.

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Autores principales:	Bo Ning, Wei Zhao, Chen Qian, Pinghua Liu, Qingtian Li, Wenyuan Li, Rong-Fu Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ce9e8507933b4b4c9760b0e18633d82d
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spelling	oai:doaj.org-article:ce9e8507933b4b4c9760b0e18633d82d2021-12-02T15:39:02ZUSP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components10.1038/s41467-017-00301-42041-1723https://doaj.org/article/ce9e8507933b4b4c9760b0e18633d82d2017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00301-4https://doaj.org/toc/2041-1723The ubiquitin-proteasome system regulates cellular reprogramming by degradation of key pluripotency factors. Here the authors report that the post-translational regulation of PRC1 components CBX4 and CBX6 by ubiquitination influences reprogramming.Bo NingWei ZhaoChen QianPinghua LiuQingtian LiWenyuan LiRong-Fu WangNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Bo Ning Wei Zhao Chen Qian Pinghua Liu Qingtian Li Wenyuan Li Rong-Fu Wang USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components
description	The ubiquitin-proteasome system regulates cellular reprogramming by degradation of key pluripotency factors. Here the authors report that the post-translational regulation of PRC1 components CBX4 and CBX6 by ubiquitination influences reprogramming.
format	article
author	Bo Ning Wei Zhao Chen Qian Pinghua Liu Qingtian Li Wenyuan Li Rong-Fu Wang
author_facet	Bo Ning Wei Zhao Chen Qian Pinghua Liu Qingtian Li Wenyuan Li Rong-Fu Wang
author_sort	Bo Ning
title	USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components
title_short	USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components
title_full	USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components
title_fullStr	USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components
title_full_unstemmed	USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components
title_sort	usp26 functions as a negative regulator of cellular reprogramming by stabilising prc1 complex components
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/ce9e8507933b4b4c9760b0e18633d82d
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_version_	1718386016893534208

USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components

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