Colorimetric detection of magnesium (II) ions using tryptophan functionalized gold nanoparticles

Abstract The functional nanoparticles with specific molecular probe appear to be a promising approach for developing colorimetric nanosensor. In this work, we have synthesized tryptophan capped gold nanoparticles (AuNPs) and used to establish colorimetric detection of magnesium (Mg2+). The colorimet...

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Autores principales:	Dae-Young Kim, Surendra Shinde, Gajanan Ghodake
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/cea46738d55a49af9c7cfcc0b7dc2a8f
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spelling	oai:doaj.org-article:cea46738d55a49af9c7cfcc0b7dc2a8f2021-12-02T15:05:34ZColorimetric detection of magnesium (II) ions using tryptophan functionalized gold nanoparticles10.1038/s41598-017-04359-42045-2322https://doaj.org/article/cea46738d55a49af9c7cfcc0b7dc2a8f2017-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-04359-4https://doaj.org/toc/2045-2322Abstract The functional nanoparticles with specific molecular probe appear to be a promising approach for developing colorimetric nanosensor. In this work, we have synthesized tryptophan capped gold nanoparticles (AuNPs) and used to establish colorimetric detection of magnesium (Mg2+). The colorimetric response of the AuNPs toward Mg2+ was noticed with naked eyes, and spectral changes were monitored by using UV-Vis spectrophotometer. The detection response was rapid (less than 1 min), with a detection limit (LOD) about 0.2 µmol L−1. The proposed nanoprobe shows characteristic red-shift of the AuNPs at 620 nm and high selectivity for Mg2+ due to the binding affinity of the tryptophan with Mg2+. The real-time response of the UV-Vis spectrum was monitored at three different concentrations of Mg2+ (0.45, 0.50, and 0.55 µmol L−1). The AuNPs probe was suitable to provide a molecular platform for selective coordination with Mg2+ over Ca2+ ions, thus it could be facile to establish a practically viable sensing system. Furthermore, experimental results were confirmed to exhibit excellent linear curve for urine and serum samples spiked with Mg2+. Thus, this nanosensor is practically useful for the detection of Mg2+, without using expensive instruments, enzymes and/or DNA molecules.Dae-Young KimSurendra ShindeGajanan GhodakeNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Dae-Young Kim Surendra Shinde Gajanan Ghodake Colorimetric detection of magnesium (II) ions using tryptophan functionalized gold nanoparticles
description	Abstract The functional nanoparticles with specific molecular probe appear to be a promising approach for developing colorimetric nanosensor. In this work, we have synthesized tryptophan capped gold nanoparticles (AuNPs) and used to establish colorimetric detection of magnesium (Mg2+). The colorimetric response of the AuNPs toward Mg2+ was noticed with naked eyes, and spectral changes were monitored by using UV-Vis spectrophotometer. The detection response was rapid (less than 1 min), with a detection limit (LOD) about 0.2 µmol L−1. The proposed nanoprobe shows characteristic red-shift of the AuNPs at 620 nm and high selectivity for Mg2+ due to the binding affinity of the tryptophan with Mg2+. The real-time response of the UV-Vis spectrum was monitored at three different concentrations of Mg2+ (0.45, 0.50, and 0.55 µmol L−1). The AuNPs probe was suitable to provide a molecular platform for selective coordination with Mg2+ over Ca2+ ions, thus it could be facile to establish a practically viable sensing system. Furthermore, experimental results were confirmed to exhibit excellent linear curve for urine and serum samples spiked with Mg2+. Thus, this nanosensor is practically useful for the detection of Mg2+, without using expensive instruments, enzymes and/or DNA molecules.
format	article
author	Dae-Young Kim Surendra Shinde Gajanan Ghodake
author_facet	Dae-Young Kim Surendra Shinde Gajanan Ghodake
author_sort	Dae-Young Kim
title	Colorimetric detection of magnesium (II) ions using tryptophan functionalized gold nanoparticles
title_short	Colorimetric detection of magnesium (II) ions using tryptophan functionalized gold nanoparticles
title_full	Colorimetric detection of magnesium (II) ions using tryptophan functionalized gold nanoparticles
title_fullStr	Colorimetric detection of magnesium (II) ions using tryptophan functionalized gold nanoparticles
title_full_unstemmed	Colorimetric detection of magnesium (II) ions using tryptophan functionalized gold nanoparticles
title_sort	colorimetric detection of magnesium (ii) ions using tryptophan functionalized gold nanoparticles
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/cea46738d55a49af9c7cfcc0b7dc2a8f
work_keys_str_mv	AT daeyoungkim colorimetricdetectionofmagnesiumiiionsusingtryptophanfunctionalizedgoldnanoparticles AT surendrashinde colorimetricdetectionofmagnesiumiiionsusingtryptophanfunctionalizedgoldnanoparticles AT gajananghodake colorimetricdetectionofmagnesiumiiionsusingtryptophanfunctionalizedgoldnanoparticles
_version_	1718388795203649536

Colorimetric detection of magnesium (II) ions using tryptophan functionalized gold nanoparticles

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