HiC-DC+ enables systematic 3D interaction calls and differential analysis for Hi-C and HiChIP

The genome-wide investigation of chromatin organization enables insights into global gene expression control. Here, the authors present a computationally efficient method for the analysis of chromatin organization data and use it to recover principles of 3D organization across conditions.

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Detalles Bibliográficos
Autores principales:	Merve Sahin, Wilfred Wong, Yingqian Zhan, Kinsey Van Deynze, Richard Koche, Christina S. Leslie
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/cea56403ca294a09940716ef0bd1c22b
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spelling	oai:doaj.org-article:cea56403ca294a09940716ef0bd1c22b2021-12-02T17:34:34ZHiC-DC+ enables systematic 3D interaction calls and differential analysis for Hi-C and HiChIP10.1038/s41467-021-23749-x2041-1723https://doaj.org/article/cea56403ca294a09940716ef0bd1c22b2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23749-xhttps://doaj.org/toc/2041-1723The genome-wide investigation of chromatin organization enables insights into global gene expression control. Here, the authors present a computationally efficient method for the analysis of chromatin organization data and use it to recover principles of 3D organization across conditions.Merve SahinWilfred WongYingqian ZhanKinsey Van DeynzeRichard KocheChristina S. LeslieNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Merve Sahin Wilfred Wong Yingqian Zhan Kinsey Van Deynze Richard Koche Christina S. Leslie HiC-DC+ enables systematic 3D interaction calls and differential analysis for Hi-C and HiChIP
description	The genome-wide investigation of chromatin organization enables insights into global gene expression control. Here, the authors present a computationally efficient method for the analysis of chromatin organization data and use it to recover principles of 3D organization across conditions.
format	article
author	Merve Sahin Wilfred Wong Yingqian Zhan Kinsey Van Deynze Richard Koche Christina S. Leslie
author_facet	Merve Sahin Wilfred Wong Yingqian Zhan Kinsey Van Deynze Richard Koche Christina S. Leslie
author_sort	Merve Sahin
title	HiC-DC+ enables systematic 3D interaction calls and differential analysis for Hi-C and HiChIP
title_short	HiC-DC+ enables systematic 3D interaction calls and differential analysis for Hi-C and HiChIP
title_full	HiC-DC+ enables systematic 3D interaction calls and differential analysis for Hi-C and HiChIP
title_fullStr	HiC-DC+ enables systematic 3D interaction calls and differential analysis for Hi-C and HiChIP
title_full_unstemmed	HiC-DC+ enables systematic 3D interaction calls and differential analysis for Hi-C and HiChIP
title_sort	hic-dc+ enables systematic 3d interaction calls and differential analysis for hi-c and hichip
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/cea56403ca294a09940716ef0bd1c22b
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HiC-DC+ enables systematic 3D interaction calls and differential analysis for Hi-C and HiChIP

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