Differential contribution of transcriptomic regulatory layers in the definition of neuronal identity

Post-transcriptional gene regulation is an important contributor to cell type-specific differences at the transcriptomic level. Here, the authors use a multiomics approach to characterize neuronal diversity in the mouse nervous system, analyzing the relative contributions of multiple layers of trans...

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Autores principales:	Kevin C. H. Ha, Timothy Sterne-Weiler, Quaid Morris, Robert J. Weatheritt, Benjamin J. Blencowe
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ceac70d961764ae2880fc4ec471358e9
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spelling	oai:doaj.org-article:ceac70d961764ae2880fc4ec471358e92021-12-02T15:22:49ZDifferential contribution of transcriptomic regulatory layers in the definition of neuronal identity10.1038/s41467-020-20483-82041-1723https://doaj.org/article/ceac70d961764ae2880fc4ec471358e92021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20483-8https://doaj.org/toc/2041-1723Post-transcriptional gene regulation is an important contributor to cell type-specific differences at the transcriptomic level. Here, the authors use a multiomics approach to characterize neuronal diversity in the mouse nervous system, analyzing the relative contributions of multiple layers of transcriptomic regulation in the specification of cell type identity.Kevin C. H. HaTimothy Sterne-WeilerQuaid MorrisRobert J. WeatherittBenjamin J. BlencoweNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kevin C. H. Ha Timothy Sterne-Weiler Quaid Morris Robert J. Weatheritt Benjamin J. Blencowe Differential contribution of transcriptomic regulatory layers in the definition of neuronal identity
description	Post-transcriptional gene regulation is an important contributor to cell type-specific differences at the transcriptomic level. Here, the authors use a multiomics approach to characterize neuronal diversity in the mouse nervous system, analyzing the relative contributions of multiple layers of transcriptomic regulation in the specification of cell type identity.
format	article
author	Kevin C. H. Ha Timothy Sterne-Weiler Quaid Morris Robert J. Weatheritt Benjamin J. Blencowe
author_facet	Kevin C. H. Ha Timothy Sterne-Weiler Quaid Morris Robert J. Weatheritt Benjamin J. Blencowe
author_sort	Kevin C. H. Ha
title	Differential contribution of transcriptomic regulatory layers in the definition of neuronal identity
title_short	Differential contribution of transcriptomic regulatory layers in the definition of neuronal identity
title_full	Differential contribution of transcriptomic regulatory layers in the definition of neuronal identity
title_fullStr	Differential contribution of transcriptomic regulatory layers in the definition of neuronal identity
title_full_unstemmed	Differential contribution of transcriptomic regulatory layers in the definition of neuronal identity
title_sort	differential contribution of transcriptomic regulatory layers in the definition of neuronal identity
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/ceac70d961764ae2880fc4ec471358e9
work_keys_str_mv	AT kevinchha differentialcontributionoftranscriptomicregulatorylayersinthedefinitionofneuronalidentity AT timothysterneweiler differentialcontributionoftranscriptomicregulatorylayersinthedefinitionofneuronalidentity AT quaidmorris differentialcontributionoftranscriptomicregulatorylayersinthedefinitionofneuronalidentity AT robertjweatheritt differentialcontributionoftranscriptomicregulatorylayersinthedefinitionofneuronalidentity AT benjaminjblencowe differentialcontributionoftranscriptomicregulatorylayersinthedefinitionofneuronalidentity
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Differential contribution of transcriptomic regulatory layers in the definition of neuronal identity

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