Mucosal BCG Vaccination Induces Protective Lung-Resident Memory T Cell Populations against Tuberculosis

Mucosal BCG Vaccination Induces Protective Lung-Resident Memory T Cell Populations against Tuberculosis

ABSTRACT Mycobacterium bovis Bacille Calmette-Guérin (BCG) is the only licensed vaccine against tuberculosis (TB), yet its moderate efficacy against pulmonary TB calls for improved vaccination strategies. Mucosal BCG vaccination generates superior protection against TB in animal models; however, the...

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Autores principales: Carolina Perdomo, Ulrike Zedler, Anja A. Kühl, Laura Lozza, Philippe Saikali, Leif E. Sander, Alexis Vogelzang, Stefan H. E. Kaufmann, Andreas Kupz
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2016
Materias:
Microbiology
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Acceso en línea:https://doaj.org/article/cec34d180c4d431fa8b85707529ae45e
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