Tumor evolutionary trajectories during the acquisition of invasiveness in early stage lung adenocarcinoma

Invasive early stage lung adenocarcinoma has a heterogeneous prognosis. Here, the authors microdissect malignant pulmonary nodules to invasive and preinvasive components and study the mutations that are common or private between the lesions, allowing them to understand the evolutionary path of the t...

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Autores principales:	Siwei Wang, Mulong Du, Jingyuan Zhang, Weizhang Xu, Qianyu Yuan, Ming Li, Jie Wang, Hongyu Zhu, Yuzhuo Wang, Cheng Wang, Yuhua Gong, Xiaonan Wang, Zhibin Hu, David C. Christiani, Lin Xu, Hongbing Shen, Rong Yin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ceca0fb06c39440fab70e429d7102414
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spelling	oai:doaj.org-article:ceca0fb06c39440fab70e429d71024142021-12-02T17:32:13ZTumor evolutionary trajectories during the acquisition of invasiveness in early stage lung adenocarcinoma10.1038/s41467-020-19855-x2041-1723https://doaj.org/article/ceca0fb06c39440fab70e429d71024142020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19855-xhttps://doaj.org/toc/2041-1723Invasive early stage lung adenocarcinoma has a heterogeneous prognosis. Here, the authors microdissect malignant pulmonary nodules to invasive and preinvasive components and study the mutations that are common or private between the lesions, allowing them to understand the evolutionary path of the tumours.Siwei WangMulong DuJingyuan ZhangWeizhang XuQianyu YuanMing LiJie WangHongyu ZhuYuzhuo WangCheng WangYuhua GongXiaonan WangZhibin HuDavid C. ChristianiLin XuHongbing ShenRong YinNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Siwei Wang Mulong Du Jingyuan Zhang Weizhang Xu Qianyu Yuan Ming Li Jie Wang Hongyu Zhu Yuzhuo Wang Cheng Wang Yuhua Gong Xiaonan Wang Zhibin Hu David C. Christiani Lin Xu Hongbing Shen Rong Yin Tumor evolutionary trajectories during the acquisition of invasiveness in early stage lung adenocarcinoma
description	Invasive early stage lung adenocarcinoma has a heterogeneous prognosis. Here, the authors microdissect malignant pulmonary nodules to invasive and preinvasive components and study the mutations that are common or private between the lesions, allowing them to understand the evolutionary path of the tumours.
format	article
author	Siwei Wang Mulong Du Jingyuan Zhang Weizhang Xu Qianyu Yuan Ming Li Jie Wang Hongyu Zhu Yuzhuo Wang Cheng Wang Yuhua Gong Xiaonan Wang Zhibin Hu David C. Christiani Lin Xu Hongbing Shen Rong Yin
author_facet	Siwei Wang Mulong Du Jingyuan Zhang Weizhang Xu Qianyu Yuan Ming Li Jie Wang Hongyu Zhu Yuzhuo Wang Cheng Wang Yuhua Gong Xiaonan Wang Zhibin Hu David C. Christiani Lin Xu Hongbing Shen Rong Yin
author_sort	Siwei Wang
title	Tumor evolutionary trajectories during the acquisition of invasiveness in early stage lung adenocarcinoma
title_short	Tumor evolutionary trajectories during the acquisition of invasiveness in early stage lung adenocarcinoma
title_full	Tumor evolutionary trajectories during the acquisition of invasiveness in early stage lung adenocarcinoma
title_fullStr	Tumor evolutionary trajectories during the acquisition of invasiveness in early stage lung adenocarcinoma
title_full_unstemmed	Tumor evolutionary trajectories during the acquisition of invasiveness in early stage lung adenocarcinoma
title_sort	tumor evolutionary trajectories during the acquisition of invasiveness in early stage lung adenocarcinoma
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/ceca0fb06c39440fab70e429d7102414
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Tumor evolutionary trajectories during the acquisition of invasiveness in early stage lung adenocarcinoma

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