Application of nanodiagnostics in point-of-care tests for infectious diseases

Yongzhong Wang,1 Li Yu,2 Xiaowei Kong,1 Leming Sun3 1Anhui Key Laboratory of Modern Biomanufacturing, School of Life Sciences, Anhui University, Hefei, Anhui, People’s Republic of China, 2Department of Microbiology and Parasitology, Anhui Provincial Laboratory of Microbiology and Parasito...

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Autores principales:	Wang YZ, Yu L, Kong XW, Sun LM
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	nanodiagnostics nanoparticles nanodevices point of care test infectious diseases pathogens Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/ced28980ff82449dae81d8cad316857c
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spelling	oai:doaj.org-article:ced28980ff82449dae81d8cad316857c2021-12-02T04:55:03ZApplication of nanodiagnostics in point-of-care tests for infectious diseases1178-2013https://doaj.org/article/ced28980ff82449dae81d8cad316857c2017-07-01T00:00:00Zhttps://www.dovepress.com/application-of-nanodiagnostics-in-point-of-care-tests-for-infectious-d-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Yongzhong Wang,1 Li Yu,2 Xiaowei Kong,1 Leming Sun3 1Anhui Key Laboratory of Modern Biomanufacturing, School of Life Sciences, Anhui University, Hefei, Anhui, People’s Republic of China, 2Department of Microbiology and Parasitology, Anhui Provincial Laboratory of Microbiology and Parasitology, Anhui Key Laboratory of Zoonoses, Anhui Medical University, Hefei, Anhui, People’s Republic of China; 3Department of Biomedical Engineering, The Ohio State University, Columbus, OH, USA Abstract: Although tremendous efforts have been put into the treatment of infectious diseases to prevent epidemics and mortality, it is still one of the major health care issues that have a profound impact on humankind. Therefore, the development of specific, sensitive, accurate, rapid, low-cost, and easy-to-use diagnostic tools is still in urgent demand. Nanodiagnostics, defined as the application of nanotechnology to medical diagnostics, can offer many unique opportunities for more successful and efficient diagnosis and treatment for infectious diseases. In this review, we provide an overview of the nanodiagnostics for infectious diseases from nanoparticle-based, nanodevice-based, and point-of-care test (POCT) platforms. Most importantly, emphasis focused on the recent trends in the nanotechnology-based POCT system. The current state-of-the-art and most promising point-of-care nanodiagnostic technologies, including miniaturized diagnostic magnetic resonance platform, magnetic barcode assay system, cell phone-based polarized light microscopy platform, cell phone-based dongle platform, and paper-based POCT platform, for infectious diseases were fully examined. The limitations, challenges, and future trends of the nanodiagnostics in POCTs for infectious diseases are also discussed. Keywords: nanodiagnostics, nanoparticles, nanodevices, point-of-care test, infectious diseases, pathogensWang YZYu LKong XWSun LMDove Medical Pressarticlenanodiagnosticsnanoparticlesnanodevicespoint of care testinfectious diseasespathogensMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol Volume 12, Pp 4789-4803 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	nanodiagnostics nanoparticles nanodevices point of care test infectious diseases pathogens Medicine (General) R5-920
spellingShingle	nanodiagnostics nanoparticles nanodevices point of care test infectious diseases pathogens Medicine (General) R5-920 Wang YZ Yu L Kong XW Sun LM Application of nanodiagnostics in point-of-care tests for infectious diseases
description	Yongzhong Wang,1 Li Yu,2 Xiaowei Kong,1 Leming Sun3 1Anhui Key Laboratory of Modern Biomanufacturing, School of Life Sciences, Anhui University, Hefei, Anhui, People’s Republic of China, 2Department of Microbiology and Parasitology, Anhui Provincial Laboratory of Microbiology and Parasitology, Anhui Key Laboratory of Zoonoses, Anhui Medical University, Hefei, Anhui, People’s Republic of China; 3Department of Biomedical Engineering, The Ohio State University, Columbus, OH, USA Abstract: Although tremendous efforts have been put into the treatment of infectious diseases to prevent epidemics and mortality, it is still one of the major health care issues that have a profound impact on humankind. Therefore, the development of specific, sensitive, accurate, rapid, low-cost, and easy-to-use diagnostic tools is still in urgent demand. Nanodiagnostics, defined as the application of nanotechnology to medical diagnostics, can offer many unique opportunities for more successful and efficient diagnosis and treatment for infectious diseases. In this review, we provide an overview of the nanodiagnostics for infectious diseases from nanoparticle-based, nanodevice-based, and point-of-care test (POCT) platforms. Most importantly, emphasis focused on the recent trends in the nanotechnology-based POCT system. The current state-of-the-art and most promising point-of-care nanodiagnostic technologies, including miniaturized diagnostic magnetic resonance platform, magnetic barcode assay system, cell phone-based polarized light microscopy platform, cell phone-based dongle platform, and paper-based POCT platform, for infectious diseases were fully examined. The limitations, challenges, and future trends of the nanodiagnostics in POCTs for infectious diseases are also discussed. Keywords: nanodiagnostics, nanoparticles, nanodevices, point-of-care test, infectious diseases, pathogens
format	article
author	Wang YZ Yu L Kong XW Sun LM
author_facet	Wang YZ Yu L Kong XW Sun LM
author_sort	Wang YZ
title	Application of nanodiagnostics in point-of-care tests for infectious diseases
title_short	Application of nanodiagnostics in point-of-care tests for infectious diseases
title_full	Application of nanodiagnostics in point-of-care tests for infectious diseases
title_fullStr	Application of nanodiagnostics in point-of-care tests for infectious diseases
title_full_unstemmed	Application of nanodiagnostics in point-of-care tests for infectious diseases
title_sort	application of nanodiagnostics in point-of-care tests for infectious diseases
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/ced28980ff82449dae81d8cad316857c
work_keys_str_mv	AT wangyz applicationofnanodiagnosticsinpointofcaretestsforinfectiousdiseases AT yul applicationofnanodiagnosticsinpointofcaretestsforinfectiousdiseases AT kongxw applicationofnanodiagnosticsinpointofcaretestsforinfectiousdiseases AT sunlm applicationofnanodiagnosticsinpointofcaretestsforinfectiousdiseases
_version_	1718401034998513664

Application of nanodiagnostics in point-of-care tests for infectious diseases

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