ISOLASI SENYAWA TRITERPENOID DAN UJI ANTIBAKTERI EKSTRAK n-HEKSAN DAUN KAYU ARA (Ficus aurata (Miq.) Miq)

Triterpenoid isolation from n-hexane extract of kayu ara leaves (Ficus aurata (Miq.) Miq) has been performed. The Isolation has been done by column chromatography method using silica gel as a stationary phase and n-hexane and ethyl acetate as mobile phase with isocratic method and it is continued by...

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Autores principales:	Adlis Santoni, Mai Efdi, Restu Bumali
Formato:	article
Lenguaje:	EN ID
Publicado:	Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Andalas 2019
Materias:	Kayu ara (Ficus aurata (Miq.) Miq) Triterpenoid Antibacterial Chemistry QD1-999 Biochemistry QD415-436
Acceso en línea:	https://doaj.org/article/ced5c7c6597c473ba3f25a442c12e6be
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spelling	oai:doaj.org-article:ced5c7c6597c473ba3f25a442c12e6be2021-12-02T10:57:46ZISOLASI SENYAWA TRITERPENOID DAN UJI ANTIBAKTERI EKSTRAK n-HEKSAN DAUN KAYU ARA (Ficus aurata (Miq.) Miq)1978-628X2476-896010.25077/jrk.v12i2.268https://doaj.org/article/ced5c7c6597c473ba3f25a442c12e6be2019-03-01T00:00:00Zhttp://jrk.fmipa.unand.ac.id/index.php/jrk/article/view/268https://doaj.org/toc/1978-628Xhttps://doaj.org/toc/2476-8960Triterpenoid isolation from n-hexane extract of kayu ara leaves (Ficus aurata (Miq.) Miq) has been performed. The Isolation has been done by column chromatography method using silica gel as a stationary phase and n-hexane and ethyl acetate as mobile phase with isocratic method and it is continued by trituration method. Isolated compound has white amorphous shape, decomposed at 86-87ºC and gives single spot with reddish brown violet in LB reagent and in H2SO4 reagent on TLC test. UV spectra indicate the presence of double bonds in the isolated compound at 204 nm λmax and IR spectra showed -OH functional group at 3290 cm-1, -CH stretching at 2912,90 cm-1, C=C at 1676 cm-1, C-O stretching at 1054,93 cm-1, and at 1374 cm-1 is spectra of geminal dimethyl compound that are characteristic of triterpenoids which supports ultraviolet spectroscopic data. Antibacterial activity test showed that isolated compound is active in inhibiting the growth of gram-positive bacteria Staphyloccocus aureus and gram-negative bacteria Escherichia coli.Adlis SantoniMai EfdiRestu BumaliDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas AndalasarticleKayu ara (Ficus aurata (Miq.) Miq)TriterpenoidAntibacterialChemistryQD1-999BiochemistryQD415-436ENIDJurnal Riset Kimia, Vol 10, Iss 1, Pp 1-8 (2019)
institution	DOAJ
collection	DOAJ
language	EN ID
topic	Kayu ara (Ficus aurata (Miq.) Miq) Triterpenoid Antibacterial Chemistry QD1-999 Biochemistry QD415-436
spellingShingle	Kayu ara (Ficus aurata (Miq.) Miq) Triterpenoid Antibacterial Chemistry QD1-999 Biochemistry QD415-436 Adlis Santoni Mai Efdi Restu Bumali ISOLASI SENYAWA TRITERPENOID DAN UJI ANTIBAKTERI EKSTRAK n-HEKSAN DAUN KAYU ARA (Ficus aurata (Miq.) Miq)
description	Triterpenoid isolation from n-hexane extract of kayu ara leaves (Ficus aurata (Miq.) Miq) has been performed. The Isolation has been done by column chromatography method using silica gel as a stationary phase and n-hexane and ethyl acetate as mobile phase with isocratic method and it is continued by trituration method. Isolated compound has white amorphous shape, decomposed at 86-87ºC and gives single spot with reddish brown violet in LB reagent and in H2SO4 reagent on TLC test. UV spectra indicate the presence of double bonds in the isolated compound at 204 nm λmax and IR spectra showed -OH functional group at 3290 cm-1, -CH stretching at 2912,90 cm-1, C=C at 1676 cm-1, C-O stretching at 1054,93 cm-1, and at 1374 cm-1 is spectra of geminal dimethyl compound that are characteristic of triterpenoids which supports ultraviolet spectroscopic data. Antibacterial activity test showed that isolated compound is active in inhibiting the growth of gram-positive bacteria Staphyloccocus aureus and gram-negative bacteria Escherichia coli.
format	article
author	Adlis Santoni Mai Efdi Restu Bumali
author_facet	Adlis Santoni Mai Efdi Restu Bumali
author_sort	Adlis Santoni
title	ISOLASI SENYAWA TRITERPENOID DAN UJI ANTIBAKTERI EKSTRAK n-HEKSAN DAUN KAYU ARA (Ficus aurata (Miq.) Miq)
title_short	ISOLASI SENYAWA TRITERPENOID DAN UJI ANTIBAKTERI EKSTRAK n-HEKSAN DAUN KAYU ARA (Ficus aurata (Miq.) Miq)
title_full	ISOLASI SENYAWA TRITERPENOID DAN UJI ANTIBAKTERI EKSTRAK n-HEKSAN DAUN KAYU ARA (Ficus aurata (Miq.) Miq)
title_fullStr	ISOLASI SENYAWA TRITERPENOID DAN UJI ANTIBAKTERI EKSTRAK n-HEKSAN DAUN KAYU ARA (Ficus aurata (Miq.) Miq)
title_full_unstemmed	ISOLASI SENYAWA TRITERPENOID DAN UJI ANTIBAKTERI EKSTRAK n-HEKSAN DAUN KAYU ARA (Ficus aurata (Miq.) Miq)
title_sort	isolasi senyawa triterpenoid dan uji antibakteri ekstrak n-heksan daun kayu ara (ficus aurata (miq.) miq)
publisher	Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Andalas
publishDate	2019
url	https://doaj.org/article/ced5c7c6597c473ba3f25a442c12e6be
work_keys_str_mv	AT adlissantoni isolasisenyawatriterpenoiddanujiantibakteriekstraknheksandaunkayuaraficusauratamiqmiq AT maiefdi isolasisenyawatriterpenoiddanujiantibakteriekstraknheksandaunkayuaraficusauratamiqmiq AT restubumali isolasisenyawatriterpenoiddanujiantibakteriekstraknheksandaunkayuaraficusauratamiqmiq
_version_	1718396419937665024

ISOLASI SENYAWA TRITERPENOID DAN UJI ANTIBAKTERI EKSTRAK n-HEKSAN DAUN KAYU ARA (Ficus aurata (Miq.) Miq)

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