Periosteum contains skeletal stem cells with high bone regenerative potential controlled by Periostin

The periosteum, a tissue lining the bone surface, and the bone marrow are known to contain bone-forming cells. Here the authors show that skeletal stem cells reside in the mouse periosteum, and that periosteal cells have common embryonic origins with bone marrow stromal/stem cells (BMSCs), but are b...

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Autores principales: Oriane Duchamp de Lageneste, Anaïs Julien, Rana Abou-Khalil, Giulia Frangi, Caroline Carvalho, Nicolas Cagnard, Corinne Cordier, Simon J. Conway, Céline Colnot
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/ced718eacbf54167bf5ebc89421705db
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spelling oai:doaj.org-article:ced718eacbf54167bf5ebc89421705db2021-12-02T14:40:07ZPeriosteum contains skeletal stem cells with high bone regenerative potential controlled by Periostin10.1038/s41467-018-03124-z2041-1723https://doaj.org/article/ced718eacbf54167bf5ebc89421705db2018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03124-zhttps://doaj.org/toc/2041-1723The periosteum, a tissue lining the bone surface, and the bone marrow are known to contain bone-forming cells. Here the authors show that skeletal stem cells reside in the mouse periosteum, and that periosteal cells have common embryonic origins with bone marrow stromal/stem cells (BMSCs), but are better at bone repair and long-term integration than BMSCs.Oriane Duchamp de LagenesteAnaïs JulienRana Abou-KhalilGiulia FrangiCaroline CarvalhoNicolas CagnardCorinne CordierSimon J. ConwayCéline ColnotNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Oriane Duchamp de Lageneste
Anaïs Julien
Rana Abou-Khalil
Giulia Frangi
Caroline Carvalho
Nicolas Cagnard
Corinne Cordier
Simon J. Conway
Céline Colnot
Periosteum contains skeletal stem cells with high bone regenerative potential controlled by Periostin
description The periosteum, a tissue lining the bone surface, and the bone marrow are known to contain bone-forming cells. Here the authors show that skeletal stem cells reside in the mouse periosteum, and that periosteal cells have common embryonic origins with bone marrow stromal/stem cells (BMSCs), but are better at bone repair and long-term integration than BMSCs.
format article
author Oriane Duchamp de Lageneste
Anaïs Julien
Rana Abou-Khalil
Giulia Frangi
Caroline Carvalho
Nicolas Cagnard
Corinne Cordier
Simon J. Conway
Céline Colnot
author_facet Oriane Duchamp de Lageneste
Anaïs Julien
Rana Abou-Khalil
Giulia Frangi
Caroline Carvalho
Nicolas Cagnard
Corinne Cordier
Simon J. Conway
Céline Colnot
author_sort Oriane Duchamp de Lageneste
title Periosteum contains skeletal stem cells with high bone regenerative potential controlled by Periostin
title_short Periosteum contains skeletal stem cells with high bone regenerative potential controlled by Periostin
title_full Periosteum contains skeletal stem cells with high bone regenerative potential controlled by Periostin
title_fullStr Periosteum contains skeletal stem cells with high bone regenerative potential controlled by Periostin
title_full_unstemmed Periosteum contains skeletal stem cells with high bone regenerative potential controlled by Periostin
title_sort periosteum contains skeletal stem cells with high bone regenerative potential controlled by periostin
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/ced718eacbf54167bf5ebc89421705db
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AT anaisjulien periosteumcontainsskeletalstemcellswithhighboneregenerativepotentialcontrolledbyperiostin
AT ranaaboukhalil periosteumcontainsskeletalstemcellswithhighboneregenerativepotentialcontrolledbyperiostin
AT giuliafrangi periosteumcontainsskeletalstemcellswithhighboneregenerativepotentialcontrolledbyperiostin
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AT simonjconway periosteumcontainsskeletalstemcellswithhighboneregenerativepotentialcontrolledbyperiostin
AT celinecolnot periosteumcontainsskeletalstemcellswithhighboneregenerativepotentialcontrolledbyperiostin
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