Tissue engineering of acellular vascular grafts capable of somatic growth in young lambs

Current vessel grafts must be surgically replaced when the recipient outgrows them. Here, Syedain et al.bioengineer a tube of acellular matrix produced from sheep fibroblasts that is capable of cellularizaton and somatic growth when transplanted into growing lambs, eliminating the need for multiple...

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Autores principales: Zeeshan Syedain, Jay Reimer, Matthew Lahti, James Berry, Sandra Johnson, Richard Bianco, Robert T. Tranquillo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/cee13bc4a6614d84bea62d30f4e2ce44
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Sumario:Current vessel grafts must be surgically replaced when the recipient outgrows them. Here, Syedain et al.bioengineer a tube of acellular matrix produced from sheep fibroblasts that is capable of cellularizaton and somatic growth when transplanted into growing lambs, eliminating the need for multiple graft surgeries.