Tissue engineering of acellular vascular grafts capable of somatic growth in young lambs

Current vessel grafts must be surgically replaced when the recipient outgrows them. Here, Syedain et al.bioengineer a tube of acellular matrix produced from sheep fibroblasts that is capable of cellularizaton and somatic growth when transplanted into growing lambs, eliminating the need for multiple...

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Autores principales: Zeeshan Syedain, Jay Reimer, Matthew Lahti, James Berry, Sandra Johnson, Richard Bianco, Robert T. Tranquillo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/cee13bc4a6614d84bea62d30f4e2ce44
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spelling oai:doaj.org-article:cee13bc4a6614d84bea62d30f4e2ce442021-12-02T15:34:11ZTissue engineering of acellular vascular grafts capable of somatic growth in young lambs10.1038/ncomms129512041-1723https://doaj.org/article/cee13bc4a6614d84bea62d30f4e2ce442016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12951https://doaj.org/toc/2041-1723Current vessel grafts must be surgically replaced when the recipient outgrows them. Here, Syedain et al.bioengineer a tube of acellular matrix produced from sheep fibroblasts that is capable of cellularizaton and somatic growth when transplanted into growing lambs, eliminating the need for multiple graft surgeries.Zeeshan SyedainJay ReimerMatthew LahtiJames BerrySandra JohnsonRichard BiancoRobert T. TranquilloNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Zeeshan Syedain
Jay Reimer
Matthew Lahti
James Berry
Sandra Johnson
Richard Bianco
Robert T. Tranquillo
Tissue engineering of acellular vascular grafts capable of somatic growth in young lambs
description Current vessel grafts must be surgically replaced when the recipient outgrows them. Here, Syedain et al.bioengineer a tube of acellular matrix produced from sheep fibroblasts that is capable of cellularizaton and somatic growth when transplanted into growing lambs, eliminating the need for multiple graft surgeries.
format article
author Zeeshan Syedain
Jay Reimer
Matthew Lahti
James Berry
Sandra Johnson
Richard Bianco
Robert T. Tranquillo
author_facet Zeeshan Syedain
Jay Reimer
Matthew Lahti
James Berry
Sandra Johnson
Richard Bianco
Robert T. Tranquillo
author_sort Zeeshan Syedain
title Tissue engineering of acellular vascular grafts capable of somatic growth in young lambs
title_short Tissue engineering of acellular vascular grafts capable of somatic growth in young lambs
title_full Tissue engineering of acellular vascular grafts capable of somatic growth in young lambs
title_fullStr Tissue engineering of acellular vascular grafts capable of somatic growth in young lambs
title_full_unstemmed Tissue engineering of acellular vascular grafts capable of somatic growth in young lambs
title_sort tissue engineering of acellular vascular grafts capable of somatic growth in young lambs
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/cee13bc4a6614d84bea62d30f4e2ce44
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