Tissue engineering of acellular vascular grafts capable of somatic growth in young lambs
Current vessel grafts must be surgically replaced when the recipient outgrows them. Here, Syedain et al.bioengineer a tube of acellular matrix produced from sheep fibroblasts that is capable of cellularizaton and somatic growth when transplanted into growing lambs, eliminating the need for multiple...
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Nature Portfolio
2016
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oai:doaj.org-article:cee13bc4a6614d84bea62d30f4e2ce442021-12-02T15:34:11ZTissue engineering of acellular vascular grafts capable of somatic growth in young lambs10.1038/ncomms129512041-1723https://doaj.org/article/cee13bc4a6614d84bea62d30f4e2ce442016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12951https://doaj.org/toc/2041-1723Current vessel grafts must be surgically replaced when the recipient outgrows them. Here, Syedain et al.bioengineer a tube of acellular matrix produced from sheep fibroblasts that is capable of cellularizaton and somatic growth when transplanted into growing lambs, eliminating the need for multiple graft surgeries.Zeeshan SyedainJay ReimerMatthew LahtiJames BerrySandra JohnsonRichard BiancoRobert T. TranquilloNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016) |
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Science Q Zeeshan Syedain Jay Reimer Matthew Lahti James Berry Sandra Johnson Richard Bianco Robert T. Tranquillo Tissue engineering of acellular vascular grafts capable of somatic growth in young lambs |
description |
Current vessel grafts must be surgically replaced when the recipient outgrows them. Here, Syedain et al.bioengineer a tube of acellular matrix produced from sheep fibroblasts that is capable of cellularizaton and somatic growth when transplanted into growing lambs, eliminating the need for multiple graft surgeries. |
format |
article |
author |
Zeeshan Syedain Jay Reimer Matthew Lahti James Berry Sandra Johnson Richard Bianco Robert T. Tranquillo |
author_facet |
Zeeshan Syedain Jay Reimer Matthew Lahti James Berry Sandra Johnson Richard Bianco Robert T. Tranquillo |
author_sort |
Zeeshan Syedain |
title |
Tissue engineering of acellular vascular grafts capable of somatic growth in young lambs |
title_short |
Tissue engineering of acellular vascular grafts capable of somatic growth in young lambs |
title_full |
Tissue engineering of acellular vascular grafts capable of somatic growth in young lambs |
title_fullStr |
Tissue engineering of acellular vascular grafts capable of somatic growth in young lambs |
title_full_unstemmed |
Tissue engineering of acellular vascular grafts capable of somatic growth in young lambs |
title_sort |
tissue engineering of acellular vascular grafts capable of somatic growth in young lambs |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/cee13bc4a6614d84bea62d30f4e2ce44 |
work_keys_str_mv |
AT zeeshansyedain tissueengineeringofacellularvasculargraftscapableofsomaticgrowthinyounglambs AT jayreimer tissueengineeringofacellularvasculargraftscapableofsomaticgrowthinyounglambs AT matthewlahti tissueengineeringofacellularvasculargraftscapableofsomaticgrowthinyounglambs AT jamesberry tissueengineeringofacellularvasculargraftscapableofsomaticgrowthinyounglambs AT sandrajohnson tissueengineeringofacellularvasculargraftscapableofsomaticgrowthinyounglambs AT richardbianco tissueengineeringofacellularvasculargraftscapableofsomaticgrowthinyounglambs AT robertttranquillo tissueengineeringofacellularvasculargraftscapableofsomaticgrowthinyounglambs |
_version_ |
1718386929568841728 |