Regenerative nanomedicine: current perspectives and future directions

Koel Chaudhury, Vishu Kumar, Jayaprakash Kandasamy, Sourav RoyChoudhurySchool of Medical Science and Technology, Indian Institute of Technology, Kharagpur, West Bengal, IndiaAbstract: Nanotechnology has considerably accelerated the growth of regenerative medicine in recent years....

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Autores principales:	Chaudhury K, Kumar V, Kandasamy J, RoyChoudhury S
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/cee1962c9e6749c5b77e87b71bae4fa6
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spelling	oai:doaj.org-article:cee1962c9e6749c5b77e87b71bae4fa62021-12-02T04:21:03ZRegenerative nanomedicine: current perspectives and future directions1178-2013https://doaj.org/article/cee1962c9e6749c5b77e87b71bae4fa62014-09-01T00:00:00Zhttp://www.dovepress.com/regenerative-nanomedicine-current-perspectives-and-future-directions-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013 Koel Chaudhury, Vishu Kumar, Jayaprakash Kandasamy, Sourav RoyChoudhurySchool of Medical Science and Technology, Indian Institute of Technology, Kharagpur, West Bengal, IndiaAbstract: Nanotechnology has considerably accelerated the growth of regenerative medicine in recent years. Application of nanotechnology in regenerative medicine has revolutionized the designing of grafts and scaffolds which has resulted in new grafts/scaffold systems having significantly enhanced cellular and tissue regenerative properties. Since the cell–cell and cell-matrix interaction in biological systems takes place at the nanoscale level, the application of nanotechnology gives an edge in modifying the cellular function and/or matrix function in a more desired way to mimic the native tissue/organ. In this review, we focus on the nanotechnology-based recent advances and trends in regenerative medicine and discussed under individual organ systems including bone, cartilage, nerve, skin, teeth, myocardium, liver and eye. Recent studies that are related to the design of various types of nanostructured scaffolds and incorporation of nanomaterials into the matrices are reported. We have also documented reports where these materials and matrices have been compared for their better biocompatibility and efficacy in supporting the damaged tissue. In addition to the recent developments, future directions and possible challenges in translating the findings from bench to bedside are outlined.Keywords: regenerative medicine, nanomedicine, nanotechnologyChaudhury KKumar VKandasamy JRoyChoudhury SDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2014, Iss Issue 1, Pp 4153-4167 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Chaudhury K Kumar V Kandasamy J RoyChoudhury S Regenerative nanomedicine: current perspectives and future directions
description	Koel Chaudhury, Vishu Kumar, Jayaprakash Kandasamy, Sourav RoyChoudhurySchool of Medical Science and Technology, Indian Institute of Technology, Kharagpur, West Bengal, IndiaAbstract: Nanotechnology has considerably accelerated the growth of regenerative medicine in recent years. Application of nanotechnology in regenerative medicine has revolutionized the designing of grafts and scaffolds which has resulted in new grafts/scaffold systems having significantly enhanced cellular and tissue regenerative properties. Since the cell–cell and cell-matrix interaction in biological systems takes place at the nanoscale level, the application of nanotechnology gives an edge in modifying the cellular function and/or matrix function in a more desired way to mimic the native tissue/organ. In this review, we focus on the nanotechnology-based recent advances and trends in regenerative medicine and discussed under individual organ systems including bone, cartilage, nerve, skin, teeth, myocardium, liver and eye. Recent studies that are related to the design of various types of nanostructured scaffolds and incorporation of nanomaterials into the matrices are reported. We have also documented reports where these materials and matrices have been compared for their better biocompatibility and efficacy in supporting the damaged tissue. In addition to the recent developments, future directions and possible challenges in translating the findings from bench to bedside are outlined.Keywords: regenerative medicine, nanomedicine, nanotechnology
format	article
author	Chaudhury K Kumar V Kandasamy J RoyChoudhury S
author_facet	Chaudhury K Kumar V Kandasamy J RoyChoudhury S
author_sort	Chaudhury K
title	Regenerative nanomedicine: current perspectives and future directions
title_short	Regenerative nanomedicine: current perspectives and future directions
title_full	Regenerative nanomedicine: current perspectives and future directions
title_fullStr	Regenerative nanomedicine: current perspectives and future directions
title_full_unstemmed	Regenerative nanomedicine: current perspectives and future directions
title_sort	regenerative nanomedicine: current perspectives and future directions
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/cee1962c9e6749c5b77e87b71bae4fa6
work_keys_str_mv	AT chaudhuryk regenerativenanomedicinecurrentperspectivesandfuturedirections AT kumarv regenerativenanomedicinecurrentperspectivesandfuturedirections AT kandasamyj regenerativenanomedicinecurrentperspectivesandfuturedirections AT roychoudhurys regenerativenanomedicinecurrentperspectivesandfuturedirections
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Regenerative nanomedicine: current perspectives and future directions

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