Programming bulk enzyme heterojunctions for biosensor development with tetrahedral DNA framework

Tetrahedral DNA framework-enabled bulk enzyme heterojunctions have been used to program biosensor interfaces. Here, the authors use DNA tetrahedrons to tether enzymes of an enzymatic cascade to gold electrodes, hence raising them over the bulk solution, which led to improved kinetics and sensitivity...

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Autores principales: Ping Song, Juwen Shen, Dekai Ye, Baijun Dong, Fei Wang, Hao Pei, Jianbang Wang, Jiye Shi, Lihua Wang, Wei Xue, Yiran Huang, Gang Huang, Xiaolei Zuo, Chunhai Fan
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/cee74c29aa11488d98d7855042329004
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spelling oai:doaj.org-article:cee74c29aa11488d98d78550423290042021-12-02T17:33:13ZProgramming bulk enzyme heterojunctions for biosensor development with tetrahedral DNA framework10.1038/s41467-020-14664-82041-1723https://doaj.org/article/cee74c29aa11488d98d78550423290042020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14664-8https://doaj.org/toc/2041-1723Tetrahedral DNA framework-enabled bulk enzyme heterojunctions have been used to program biosensor interfaces. Here, the authors use DNA tetrahedrons to tether enzymes of an enzymatic cascade to gold electrodes, hence raising them over the bulk solution, which led to improved kinetics and sensitivity.Ping SongJuwen ShenDekai YeBaijun DongFei WangHao PeiJianbang WangJiye ShiLihua WangWei XueYiran HuangGang HuangXiaolei ZuoChunhai FanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ping Song
Juwen Shen
Dekai Ye
Baijun Dong
Fei Wang
Hao Pei
Jianbang Wang
Jiye Shi
Lihua Wang
Wei Xue
Yiran Huang
Gang Huang
Xiaolei Zuo
Chunhai Fan
Programming bulk enzyme heterojunctions for biosensor development with tetrahedral DNA framework
description Tetrahedral DNA framework-enabled bulk enzyme heterojunctions have been used to program biosensor interfaces. Here, the authors use DNA tetrahedrons to tether enzymes of an enzymatic cascade to gold electrodes, hence raising them over the bulk solution, which led to improved kinetics and sensitivity.
format article
author Ping Song
Juwen Shen
Dekai Ye
Baijun Dong
Fei Wang
Hao Pei
Jianbang Wang
Jiye Shi
Lihua Wang
Wei Xue
Yiran Huang
Gang Huang
Xiaolei Zuo
Chunhai Fan
author_facet Ping Song
Juwen Shen
Dekai Ye
Baijun Dong
Fei Wang
Hao Pei
Jianbang Wang
Jiye Shi
Lihua Wang
Wei Xue
Yiran Huang
Gang Huang
Xiaolei Zuo
Chunhai Fan
author_sort Ping Song
title Programming bulk enzyme heterojunctions for biosensor development with tetrahedral DNA framework
title_short Programming bulk enzyme heterojunctions for biosensor development with tetrahedral DNA framework
title_full Programming bulk enzyme heterojunctions for biosensor development with tetrahedral DNA framework
title_fullStr Programming bulk enzyme heterojunctions for biosensor development with tetrahedral DNA framework
title_full_unstemmed Programming bulk enzyme heterojunctions for biosensor development with tetrahedral DNA framework
title_sort programming bulk enzyme heterojunctions for biosensor development with tetrahedral dna framework
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/cee74c29aa11488d98d7855042329004
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