CRISPR/cas9-mediated overexpression of long non-coding RNA SRY-box transcription factor 21 antisense divergent transcript 1 regulates the proliferation of osteosarcoma by increasing the expression of mechanistic target of rapamycin kinase and Kruppel like factor 4

Osteosarcoma is derived from primitive mesenchymal cells and is the most common primary solid malignant tumor of bone. The cause of osteosarcoma is unclear. In recent years, the role of non-coding sequences in regulating protein expression in tumors has been paid more and more attention, especially...

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Autores principales: Weiying Zhang, Qiang Wang, Haibo Du, Shichao Jiang
Formato: article
Lenguaje:EN
Publicado: Taylor & Francis Group 2021
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Acceso en línea:https://doaj.org/article/cee7dfa879014c659edae445c2f9e415
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