Validation of nasospheroids to assay CFTR functionality and modulator responses in cystic fibrosis

Validation of nasospheroids to assay CFTR functionality and modulator responses in cystic fibrosis

Abstract The availability of a simple, robust and non-invasive in vitro airway model would be useful to study the functionality of the cystic fibrosis transmembrane regulator (CFTR) protein and to personalize modulator therapy for cystic fibrosis (CF) patients. Our aim was to validate a CFTR functio...

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Autores principales: Maite Calucho, Silvia Gartner, Paula Barranco, Paula Fernández-Álvarez, Raquel García Pérez, Eduardo F. Tizzano
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/ceebc254ff6749ddae89f16c9505710e
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