Mapping genomic and transcriptomic alterations spatially in epithelial cells adjacent to human breast carcinoma

Studying the spatial mutational and gene expression alterations in breast cancer could impact our understanding of breast cancer development. Here, the authors analyse a unique dataset of epithelial samples that highlight potential field cancerisation surrounding the primary tumour.

Guardado en:
Detalles Bibliográficos
Autores principales: Moustafa Abdalla, Danh Tran-Thanh, Juan Moreno, Vladimir Iakovlev, Ranju Nair, Nisha Kanwar, Mohamed Abdalla, Jennifer P. Y. Lee, Jennifer Yin Yee Kwan, Thomas R. Cawthorn, Keisha Warren, Nona Arneson, Dong-Yu Wang, Natalie S. Fox, Bruce J. Youngson, Naomi A. Miller, Alexandra M. Easson, David McCready, Wey L. Leong, Paul C. Boutros, Susan J. Done
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/ceecba4deac145a6bb91d719ca0af931
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:ceecba4deac145a6bb91d719ca0af931
record_format dspace
spelling oai:doaj.org-article:ceecba4deac145a6bb91d719ca0af9312021-12-02T15:38:57ZMapping genomic and transcriptomic alterations spatially in epithelial cells adjacent to human breast carcinoma10.1038/s41467-017-01357-y2041-1723https://doaj.org/article/ceecba4deac145a6bb91d719ca0af9312017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01357-yhttps://doaj.org/toc/2041-1723Studying the spatial mutational and gene expression alterations in breast cancer could impact our understanding of breast cancer development. Here, the authors analyse a unique dataset of epithelial samples that highlight potential field cancerisation surrounding the primary tumour.Moustafa AbdallaDanh Tran-ThanhJuan MorenoVladimir IakovlevRanju NairNisha KanwarMohamed AbdallaJennifer P. Y. LeeJennifer Yin Yee KwanThomas R. CawthornKeisha WarrenNona ArnesonDong-Yu WangNatalie S. FoxBruce J. YoungsonNaomi A. MillerAlexandra M. EassonDavid McCreadyWey L. LeongPaul C. BoutrosSusan J. DoneNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Moustafa Abdalla
Danh Tran-Thanh
Juan Moreno
Vladimir Iakovlev
Ranju Nair
Nisha Kanwar
Mohamed Abdalla
Jennifer P. Y. Lee
Jennifer Yin Yee Kwan
Thomas R. Cawthorn
Keisha Warren
Nona Arneson
Dong-Yu Wang
Natalie S. Fox
Bruce J. Youngson
Naomi A. Miller
Alexandra M. Easson
David McCready
Wey L. Leong
Paul C. Boutros
Susan J. Done
Mapping genomic and transcriptomic alterations spatially in epithelial cells adjacent to human breast carcinoma
description Studying the spatial mutational and gene expression alterations in breast cancer could impact our understanding of breast cancer development. Here, the authors analyse a unique dataset of epithelial samples that highlight potential field cancerisation surrounding the primary tumour.
format article
author Moustafa Abdalla
Danh Tran-Thanh
Juan Moreno
Vladimir Iakovlev
Ranju Nair
Nisha Kanwar
Mohamed Abdalla
Jennifer P. Y. Lee
Jennifer Yin Yee Kwan
Thomas R. Cawthorn
Keisha Warren
Nona Arneson
Dong-Yu Wang
Natalie S. Fox
Bruce J. Youngson
Naomi A. Miller
Alexandra M. Easson
David McCready
Wey L. Leong
Paul C. Boutros
Susan J. Done
author_facet Moustafa Abdalla
Danh Tran-Thanh
Juan Moreno
Vladimir Iakovlev
Ranju Nair
Nisha Kanwar
Mohamed Abdalla
Jennifer P. Y. Lee
Jennifer Yin Yee Kwan
Thomas R. Cawthorn
Keisha Warren
Nona Arneson
Dong-Yu Wang
Natalie S. Fox
Bruce J. Youngson
Naomi A. Miller
Alexandra M. Easson
David McCready
Wey L. Leong
Paul C. Boutros
Susan J. Done
author_sort Moustafa Abdalla
title Mapping genomic and transcriptomic alterations spatially in epithelial cells adjacent to human breast carcinoma
title_short Mapping genomic and transcriptomic alterations spatially in epithelial cells adjacent to human breast carcinoma
title_full Mapping genomic and transcriptomic alterations spatially in epithelial cells adjacent to human breast carcinoma
title_fullStr Mapping genomic and transcriptomic alterations spatially in epithelial cells adjacent to human breast carcinoma
title_full_unstemmed Mapping genomic and transcriptomic alterations spatially in epithelial cells adjacent to human breast carcinoma
title_sort mapping genomic and transcriptomic alterations spatially in epithelial cells adjacent to human breast carcinoma
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/ceecba4deac145a6bb91d719ca0af931
work_keys_str_mv AT moustafaabdalla mappinggenomicandtranscriptomicalterationsspatiallyinepithelialcellsadjacenttohumanbreastcarcinoma
AT danhtranthanh mappinggenomicandtranscriptomicalterationsspatiallyinepithelialcellsadjacenttohumanbreastcarcinoma
AT juanmoreno mappinggenomicandtranscriptomicalterationsspatiallyinepithelialcellsadjacenttohumanbreastcarcinoma
AT vladimiriakovlev mappinggenomicandtranscriptomicalterationsspatiallyinepithelialcellsadjacenttohumanbreastcarcinoma
AT ranjunair mappinggenomicandtranscriptomicalterationsspatiallyinepithelialcellsadjacenttohumanbreastcarcinoma
AT nishakanwar mappinggenomicandtranscriptomicalterationsspatiallyinepithelialcellsadjacenttohumanbreastcarcinoma
AT mohamedabdalla mappinggenomicandtranscriptomicalterationsspatiallyinepithelialcellsadjacenttohumanbreastcarcinoma
AT jenniferpylee mappinggenomicandtranscriptomicalterationsspatiallyinepithelialcellsadjacenttohumanbreastcarcinoma
AT jenniferyinyeekwan mappinggenomicandtranscriptomicalterationsspatiallyinepithelialcellsadjacenttohumanbreastcarcinoma
AT thomasrcawthorn mappinggenomicandtranscriptomicalterationsspatiallyinepithelialcellsadjacenttohumanbreastcarcinoma
AT keishawarren mappinggenomicandtranscriptomicalterationsspatiallyinepithelialcellsadjacenttohumanbreastcarcinoma
AT nonaarneson mappinggenomicandtranscriptomicalterationsspatiallyinepithelialcellsadjacenttohumanbreastcarcinoma
AT dongyuwang mappinggenomicandtranscriptomicalterationsspatiallyinepithelialcellsadjacenttohumanbreastcarcinoma
AT nataliesfox mappinggenomicandtranscriptomicalterationsspatiallyinepithelialcellsadjacenttohumanbreastcarcinoma
AT brucejyoungson mappinggenomicandtranscriptomicalterationsspatiallyinepithelialcellsadjacenttohumanbreastcarcinoma
AT naomiamiller mappinggenomicandtranscriptomicalterationsspatiallyinepithelialcellsadjacenttohumanbreastcarcinoma
AT alexandrameasson mappinggenomicandtranscriptomicalterationsspatiallyinepithelialcellsadjacenttohumanbreastcarcinoma
AT davidmccready mappinggenomicandtranscriptomicalterationsspatiallyinepithelialcellsadjacenttohumanbreastcarcinoma
AT weylleong mappinggenomicandtranscriptomicalterationsspatiallyinepithelialcellsadjacenttohumanbreastcarcinoma
AT paulcboutros mappinggenomicandtranscriptomicalterationsspatiallyinepithelialcellsadjacenttohumanbreastcarcinoma
AT susanjdone mappinggenomicandtranscriptomicalterationsspatiallyinepithelialcellsadjacenttohumanbreastcarcinoma
_version_ 1718386017107443712